Notch1 抗体
(Notch 1 (NOTCH1))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
NOTCH1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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Popular Notch1 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse
Application
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Validations
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- (4)
Cat. No.
ABIN807924
Quantity
0.1 mg
Datasheet
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Reactivity
Human, Mouse
Application
FACS
Validations
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- (4)
Cat. No.
ABIN2749161
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN1686639
Quantity
100 μg
Datasheet
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Reactivity
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Application
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Cat. No.
ABIN2483201
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN2483200
Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN2483204
Quantity
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Datasheet
Datasheet
Reactivity
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Quantity
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Datasheet
Datasheet
Reactivity
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Validations
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IF, ICC
Validations
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Cat. No.
ABIN2483192
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IF, ICC
Validations
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Cat. No.
ABIN2483189
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN4912269
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC, IF
Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Notch1 抗体
: "Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway." in: Scientific reports, Vol. 10, Issue 1, pp. 5708, (2020) (PubMed).: "Enhanced lysosomal degradation maintains the quiescent state of neural stem cells." in: Nature communications, Vol. 10, Issue 1, pp. 5446, (2019) (PubMed).
: "Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling." in: Cell stem cell, Vol. 23, Issue 4, pp. 530-543.e9, (2018) (PubMed).
: "Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations." in: Scientific reports, Vol. 8, Issue 1, pp. 17987, (2018) (PubMed).
: "Prognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastases." in: Clinical oral investigations, (2017) (PubMed).
: "NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 4, pp. 1106-1119, (2017) (PubMed).
: "Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning." in: Developmental cell, Vol. 40, Issue 5, pp. 505-511.e6, (2017) (PubMed).
: "Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1." in: The Journal of biological chemistry, Vol. 292, Issue 2, pp. 732-747, (2017) (PubMed).
: "Chlamydia and ocular adnexal lymphomas: An Indian experience." in: Experimental and molecular pathology, Vol. 101, Issue 1, pp. 74-80, (2016) (PubMed).
: "Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation." in: Tumour biology, Vol. 37, Issue 10, pp. 13695-13704, (2016) (PubMed).
Aliases for Notch1 抗体
notch 1 (notch1) 抗体fibropellin-1 (LOC100631526) 抗体
Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) 抗体
notch 1 (NOTCH1) 抗体
Notch homolog 1, translocation-associated (NOTCH1) 抗体
notch 1 (Notch1) 抗体
notch 1 S homeolog (notch1.S) 抗体
9930111A19Rik 抗体
hn1 抗体
hN1 抗体
lin-12 抗体
Mis6 抗体
N1 抗体
notch 抗体
NOTCH 抗体
notch-1 抗体
notch1 抗体
NOTCH1 抗体
notch1-a 抗体
tan1 抗体
TAN1 抗体
Tan1 抗体
xnotch 抗体
xnotch1 抗体
xotch 抗体
Xotch 抗体
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