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NONO 产品

(Non-POU Domain Containing, Octamer-Binding (NONO))

Categories

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009].

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Featured NONO Categories

NONO 抗体

High quality antibodies with extensive validation data.

NONO ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NONO 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NONO 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Mouse
Application WB, IHC, IF, IHC (p)
Validations
  • (11)
Cat. No. ABIN1491072
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (18)
Cat. No. ABIN1491073
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (10)
Cat. No. ABIN6144713
Quantity 100 μL
Datasheet Datasheet

Recommended NONO ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958220
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657428
Quantity 96 tests
Datasheet Datasheet

Recommended NONO 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312785
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409494
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094215
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NONO Products

Wang, Grunseich, Fox, Burdick, Zhu, Ravazian, Hafner, Cheung: "Human proteins that interact with RNA/DNA hybrids." in: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).

Hashiramoto, Konishi, Murayama, Kawasaki, Yoshida, Tsumiyama, Tanaka, Mizuhara, Shiotsuki, Kitamura, Komai, Kimura, Yagita, Shiozawa, Shiozawa: "A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell." in: The Journal of biological chemistry, Vol. 293, Issue 6, pp. 1933-1943, (2017) (PubMed).

Lu, Sewer: "p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation." in: Molecular and cellular biology, Vol. 35, Issue 7, pp. 1223-37, (2015) (PubMed).

Chaoui, Kavo, Baral, Watanabe, Lecerf, Colley, Mendoza-Londono, Pingault, Bondurand: "Subnuclear re-localization of SOX10 and p54NRB correlates with a unique neurological phenotype associated with SOX10 missense mutations." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4933-47, (2015) (PubMed).

Isabelle, Gagné, Gallouzi, Poirier: "Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation." in: Journal of cell science, Vol. 125, Issue Pt 19, pp. 4555-66, (2012) (PubMed).

Krietsch, Caron, Gagné, Ethier, Vignard, Vincent, Rouleau, Hendzel, Poirier, Masson: "PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks." in: Nucleic acids research, Vol. 40, Issue 20, pp. 10287-301, (2012) (PubMed).

Tsofack, Garand, Sereduk, Chow, Aziz, Guay, Yin, Lebel: "NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines." in: Molecular cancer, Vol. 10, pp. 145, (2011) (PubMed).

Bubenik, Ladd, Gerber, Budiman, Driscoll: "Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2." in: RNA biology, Vol. 6, Issue 1, pp. 73-83, (2009) (PubMed).

Zhang, Zhang, Shen, Burks, Zhang, Wang, LeMaire, Yoshimura, Aoki, Coselli, Wang: "TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 27, Issue 8, pp. 1760-7, (2007) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonyms and alternative names related to NONO

non-POU domain containing octamer binding (NONO), non-POU domain containing, octamer-binding (NONO), non-POU domain containing, octamer-binding (Nono), non-POU domain containing, octamer binding L homeolog (nono.L), non-POU-domain-containing, octamer binding protein (Nono), AA407051, AV149256, NMT55, nmt55, nonA, NRB54, nrb54, P54, P54NRB, p54nrb, xp54nrb

Protein level used designations for NONO

  • 54 kDa nuclear RNA- and DNA-binding protein
  • 55 kDa nuclear protein
  • DNA-binding p52/p100 complex, 52 kDa subunit
  • non-POU domain-containing octamer (ATGCAAAT) binding protein
  • non-POU domain-containing octamer-binding protein
  • p54(nrb)
  • non-POU-domain-containing, octamer-binding protein
  • 54 kD nuclear RNA-binding protein
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