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NMT1 产品

(N-Myristoyltransferase 1 (NMT1))

Categories

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT\; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1\; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008].

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Featured NMT1 Categories

NMT1 抗体

High quality antibodies with extensive validation data.

NMT1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NMT1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NMT1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7264684
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7239278
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7154254
Quantity 100 μg
Datasheet Datasheet

Recommended NMT1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968779
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968778
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1135290
Quantity 96 tests
Datasheet Datasheet

Recommended NMT1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312726
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623711
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084581
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NMT1 Products

Thinon, Serwa, Broncel, Brannigan, Brassat, Wright, Heal, Wilkinson, Mann, Tate: "Global profiling of co- and post-translationally N-myristoylated proteomes in human cells." in: Nature communications, Vol. 5, pp. 4919, (2014) (PubMed).

Kumar, Sharma: "An improved method and cost effective strategy for soluble expression and purification of human N-myristoyltransferase 1 in E. coli." in: Molecular and cellular biochemistry, Vol. 392, Issue 1-2, pp. 175-86, (2014) (PubMed).

Takamune, Gota, Misumi, Tanaka, Okinaka, Shoji: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).

Lindwasser, Resh: "Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13037-42, (2002) (PubMed).

Shiraishi, Misumi, Takama, Takahashi, Shoji: "Myristoylation of human immunodeficiency virus type 1 gag protein is required for efficient env protein transportation to the surface of cells." in: Biochemical and biophysical research communications, Vol. 282, Issue 5, pp. 1201-5, (2001) (PubMed).

Kolluri, Balduf, Hofmann, Göttlicher: "Novel target genes of the Ah (dioxin) receptor: transcriptional induction of N-myristoyltransferase 2." in: Cancer research, Vol. 61, Issue 23, pp. 8534-9, (2001) (PubMed).

Synonyms and alternative names related to NMT1

N-myristoyltransferase 1 (NMT1), N-myristoyltransferase 1a (nmt1a), N-myristoyltransferase 1 L homeolog (nmt1.L), N-myristoyltransferase 1 (nmt1), N-myristoyltransferase 1 (predicted) (SPBC2G2.11), N-myristoyltransferase 1 (Nmt1), myristoyl-CoA:protein N-myristoyltransferase (NMT1), ARABIDOPSIS THALIANA MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE, ATNMT1, AW536594, im:2601337, MGC145283, MHM17.15, MHM17_15, myristoyl-CoA:protein N-myristoyltransferase, N-MYRISTOYLTRANSFERASE 1, NMT, nmt1, wu:fc15d01, wu:fc18a04, zgc:110714

Protein level used designations for NMT1

  • NMT 1
  • alternative, short form NMT-S
  • glycylpeptide N-tetradecanoyltransferase 1
  • long form, NMT-L
  • myristoyl-CoA:protein N-myristoyltransferase 1
  • peptide N-myristoyltransferase 1
  • type I N-myristoyltransferase
  • N-myristoyltransferase 1
  • glycylpeptide N-tetradecanoyltransferase 1-like
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