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NLRP7 产品

(NLR Family, Pyrin Domain Containing 7 (NLRP7))

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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured NLRP7 Categories

NLRP7 抗体

High quality antibodies with extensive validation data.

Recommended NLRP7 抗体

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Reactivity Human
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Cat. No. ABIN7160835
Quantity 100 μg
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Reactivity Human
Application ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
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Cat. No. ABIN872347
Quantity 100 μL
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Reactivity Human
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Cat. No. ABIN908467
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Recommended NLRP7 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6960726
Quantity 96 tests
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Recommended NLRP7 蛋白

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Source Tobacco (Nicotiana tabacum)
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Latest Publications for our NLRP7 Products

Khare, Radian, Dorfleutner, Stehlik: "Measuring NLR Oligomerization I: Size Exclusion Chromatography, Co-immunoprecipitation, and Cross-Linking." in: Methods in molecular biology (Clifton, N.J.), Vol. 1417, pp. 131-43, (2016) (PubMed).

Mahadevan, Wen, Wan, Peng, Otta, Liu, Iacovino, Mahen, Kyba, Sadikovic, Van den Veyver: "NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation." in: Human molecular genetics, Vol. 23, Issue 3, pp. 706-16, (2014) (PubMed).

Akoury, Zhang, Ao, Slim: "NLRP7 and KHDC3L, the two maternal-effect proteins responsible for recurrent hydatidiform moles, co-localize to the oocyte cytoskeleton." in: Human reproduction (Oxford, England), Vol. 30, Issue 1, pp. 159-69, (2014) (PubMed).

Reddy, Akoury, Phuong Nguyen, Abdul-Rahman, Dery, Gupta, Daley, Ao, Landolsi, Ann Fisher, Touitou, Slim: "Report of four new patients with protein-truncating mutations in C6orf221/KHDC3L and colocalization with NLRP7." in: European journal of human genetics : EJHG, Vol. 21, Issue 9, pp. 957-64, (2013) (PubMed).

Synonyms and alternative names related to NLRP7

NLR family pyrin domain containing 7 (NLRP7), CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3

Protein level used designations for NLRP7

  • NACHT, LRR and PYD containing protein 7
  • NACHT, LRR and PYD domains-containing protein 7
  • NACHT, leucine rich repeat and PYD containing 7
  • PYRIN-containing Apaf1-like protein 3
  • nucleotide-binding oligomerization domain protein 12
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
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