NLK.2 蛋白
(Nemo-Like Kinase, Gene 2 (NLK.2))
Negatively regulates Wnt/beta-catenin-signaling during development. Plays a role together with sox11 in neural induction during early embryogenesis. Involved in TGFbeta-mediated mesoderm induction in early embryos, acting downstream of map3k7/tak1 to phosphorylate stat3.1. Augments the rnf138/narf-directed ubiquitination and degradation of tcf/lef by enhancing the association of rnf138/narf and tcf/lef. Phosphorylates mef2a to play a role in anterior neural development, including eye formation.
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Recommended NLK.2 蛋白
Synonyms and alternative names related to NLK.2
nemo-like kinase, gene 2 S homeolog (nlk.2.S), nlk, xnlkProtein level used designations for NLK.2
- Nemo-like kinase 2
- Serine/threonine protein kinase NLK2
- serine/threonine-protein kinase NLK2
You are here:
