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NKX6-1 产品

(NK6 Homeobox 1 (NKX6-1))
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008].

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Featured NKX6-1 Categories

NKX6-1 抗体

High quality antibodies with extensive validation data.

NKX6-1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NKX6-1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NKX6-1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (4)
Cat. No. ABIN6940213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (2)
Cat. No. ABIN7436357
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN518370
Quantity 100 μg
Datasheet Datasheet

Recommended NKX6-1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958207
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657417
Quantity 96 tests
Datasheet Datasheet

Recommended NKX6-1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399076
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084441
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128039
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NKX6-1 Products

Griffiths, Crick, Meljon, Theofilopoulos, Abdel-Khalik, Yutuc, Parker, Kelly, Kelly, Arenas, Wang: "Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 2, pp. 191-211, (2019) (PubMed).

Wilson, Spaeth, Karp, Stocks, Hoopes, Stein, Moore: "B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib." in: JCI insight, Vol. 5, (2019) (PubMed).

Wang, Sterr, Ansarullah, Burtscher, Böttcher, Beckenbauer, Siehler, Meitinger, Häring, Staiger, Cernilogar, Schotta, Irmler, Beckers, Wright, Bakhti, Lickert: "Point mutations in the PDX1 transactivation domain impair human β-cell development and function." in: Molecular metabolism, Vol. 24, pp. 80-97, (2019) (PubMed).

Spaeth, Liu, Peters, Guo, Osipovich, Mohammadi, Roy, Bhushan, Magnuson, Hebrok, Wright, Stein: "The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function." in: Diabetes, (2019) (PubMed).

Vethe, Ghila, Berle, Hoareau, Haaland, Scholz, Paulo, Chera, Ræder: "The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation." in: Frontiers in endocrinology, Vol. 10, pp. 293, (2019) (PubMed).

Wang, Malinowski, Beckenbauer, Siehler, Blöchinger, Meitinger, Häring, Staiger, Burtscher, Lickert: "Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual." in: Stem cell research, Vol. 39, pp. 101531, (2019) (PubMed).

Mohan, Radha, Nguyen, Stawiski, Pahuja, Goldstein, Tom, Anjana, Kong-Beltran, Bhangale, Jahnavi, Chandni, Gayathri, George, Zhang, Murugan, Phalke, Chaudhuri, Gupta, Zhang, Santhosh, Stinson et al.: "Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India. ..." in: BMC medical genetics, Vol. 19, Issue 1, pp. 22, (2018) (PubMed).

Spaeth, Gupte, Perelis, Yang, Cyphert, Guo, Liu, Guo, Bass, Magnuson, Wright, Stein: "Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning." in: Diabetes, (2017) (PubMed).

Bader, Migliorini, Gegg, Moruzzi, Gerdes, Roscioni, Bakhti, Brandl, Irmler, Beckers, Aichler, Feuchtinger, Leitzinger, Zischka, Wang-Sattler, Jastroch, Tschöp, Machicao, Staiger, Häring, Chmelova et al.: "Identification of proliferative and mature β-cells in the islets of Langerhans. ..." in: Nature, Vol. 535, Issue 7612, pp. 430-4, (2016) (PubMed).

Theofilopoulos, Griffiths, Crick, Yang, Meljon, Ogundare, Kitambi, Lockhart, Tuschl, Clayton, Morris, Martinez, Reddy, Martinuzzi, Bassi, Honda, Mizuochi, Kimura, Nittono, De Michele, Carbone et al.: "Cholestenoic acids regulate motor neuron survival via liver X receptors. ..." in: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4829-42, (2014) (PubMed).

Synonyms and alternative names related to NKX6-1

NK6 homeobox 1 (nkx6-1), NK6 homeobox 1 (NKX6-1), NK6 homeobox 1 (nkx6.1), NK6 homeobox 1 L homeolog (nkx6-1.L), NK6 homeobox 1 (Nkx6-1), nkx6.1, NKX6.1, Nkx6.1, nkx6a, NKX6A, Nkx6a, Nkx61, zgc:92879

Protein level used designations for NKX6-1

  • NK6 transcription factor related, locus 1
  • NK6 homeobox 1
  • NK homeo box, family 6, member A
  • NK homeobox, family 6, A
  • NK6 transcription factor homolog A
  • homeobox protein NK-6 homolog A
  • homeobox protein Nkx-6.1
  • NK6 transcription factor related locus 1
  • Drosophila NK transcription factor related, gene family 6, locus 1
  • homeodomain transcription factor Nkx6.1
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