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Nischarin 抗体

(Nischarin (NISCH))

This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis\; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013].

recommended

Nischarin 抗体 (AA 500-700) (ABIN7161622)

NISCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

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recommended

Nischarin 抗体 (AA 1246-1345) (ABIN524609)

NISCH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated

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recommended

Nischarin 抗体 (AA 1246-1346) (ABIN1869472)

NISCH 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

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Nischarin 抗体 by 适用

Find Nischarin 抗体 for a variety of species such as anti-Human Nischarin, anti-Mouse Nischarin, anti-Rat Nischarin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nischarin 抗体 by 应用范围

Find Nischarin 抗体 validated for a specific application such as WB, ELISA, IHC, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Nischarin 抗体 by 抗体来源

Find Nischarin 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

Nischarin 抗体 by 抗原表位

Find Nischarin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Nischarin 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Nischarin 抗体. Click on a link to go to the corresponding products.

Nischarin 抗体 by 克隆

Find Nischarin 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Popular Nischarin 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Nischarin 抗体 (AA 500-700)

Reactivity Human

Application ELISA, IHC

Validations

Cat. No. ABIN7161622

Quantity 100 μL

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1246-1345)

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN524609

Quantity 100 μg

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1246-1346)

Reactivity Human

Application WB, IHC, ICC

Validations

Cat. No. ABIN1869472

Quantity 100 μL

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1335-1435)

Reactivity Mouse

Application WB, IHC, ICC

Validations

Cat. No. ABIN1980473

Quantity 100 μL

Datasheet Datasheet

anti-Nischarin 抗体 (AA 5-38)

Reactivity Human, Mouse

Application WB

Validations

Cat. No. ABIN6242733

Quantity 200 μL

Datasheet Datasheet

anti-Nischarin 抗体

Reactivity Human, Mouse, Rat

Application WB, ELISA, IP

Validations

Cat. No. ABIN7116889

Quantity 100 μg

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1335-1435)

Reactivity Mouse

Application WB

Validations

Cat. No. ABIN2586261

Quantity 100 μL

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1100-1150)

Reactivity Human

Application IP

Validations

Cat. No. ABIN7451170

Quantity 100 μg

Datasheet Datasheet

anti-Nischarin 抗体

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN7135234

Quantity 100 μL

Datasheet Datasheet

anti-Nischarin 抗体 (AA 1246-1346)

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN2327371

Quantity 100 μg

Datasheet Datasheet

anti-Nischarin 抗体

Reactivity Human

Application WB, IHC, IP, IF/ICC

Validations

Cat. No. ABIN6335986

Quantity 1 mL

Datasheet Datasheet

Latest Publications for our Nischarin 抗体

Alahari, Nasrallah: "A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 449-57, (2004) (PubMed).

Alahari, Reddig, Juliano: "The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK." in: The EMBO journal, Vol. 23, Issue 14, pp. 2777-88, (2004) (PubMed).

Juliano, Reddig, Alahari, Edin, Howe, Aplin: "Integrin regulation of cell signalling and motility." in: Biochemical Society transactions, Vol. 32, Issue Pt3, pp. 443-6, (2004) (PubMed).

Alahari: "Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK." in: Experimental cell research, Vol. 288, Issue 2, pp. 415-24, (2003) (PubMed).

Alahari, Lee, Juliano: "Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration." in: The Journal of cell biology, Vol. 151, Issue 6, pp. 1141-54, (2001) (PubMed).

Aliases for Nischarin 抗体

nischarin (NISCH) 抗体
nischarin (Cyan7822_6841) 抗体
nischarin S homeolog (nisch.S) 抗体
nischarin (nisch) 抗体
nischarin (Nisch) 抗体
1200007D05Rik 抗体
3202002H23Rik 抗体
AW494485 抗体
hIRAS 抗体
I-1 抗体
IR1 抗体
IRAS 抗体
NISCH 抗体

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Popular Nischarin 抗体

Latest Publications for our Nischarin 抗体

Aliases for Nischarin 抗体

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