NFYA 产品
(Nuclear Transcription Factor Y, alpha (NFYA))
Categories
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008].
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Featured NFYA Categories
NFYA 抗体
High quality antibodies with extensive validation data.
NFYA ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NFYA 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NFYA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257371
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6735785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN104769
Quantity
100 μg
Datasheet
Datasheet
Recommended NFYA ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5648500
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5526700
Quantity
96 tests
Datasheet
Datasheet
Recommended NFYA 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124216
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312517
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312515
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our NFYA Products
: "p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma." in: Molecular cancer, Vol. 18, Issue 1, pp. 38, (2019) (PubMed).: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).
: "Regulation of the p53 transcriptional response by structurally diverse core promoters." in: Genes & development, Vol. 24, Issue 2, pp. 135-47, (2010) (PubMed).
: "Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5203-13, (2008) (PubMed).
: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." in: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).
: "Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15628-37, (2008) (PubMed).
: "Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 984-94, (2008) (PubMed).
: "Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site." in: Journal of cellular physiology, Vol. 211, Issue 1, pp. 183-8, (2007) (PubMed).
: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).
: "Transcriptional modulation of the pre-implantation embryo-specific Rnf35 gene by the Y-box protein NF-Y/CBF." in: The Biochemical journal, Vol. 387, Issue Pt 2, pp. 367-75, (2005) (PubMed).
Synonyms and alternative names related to NFYA
nuclear transcription factor Y, alpha (nfya), nuclear transcription factor Y subunit alpha (NFYA), nuclear transcription factor-Y alpha (Nfya), nuclear transcription factor Y subunit alpha (Nfya), AA407810, CBF-A, CBF-B, Cbf-b, HAP2, ik:tdsubc_2b6, NF-YA, NFYA, SEZ-10, SEZ10, wu:fb16e03, xx:tdsubc_2b6Protein level used designations for NFYA
- fb16e03
- tdsubc_2b6
- nuclear transcription factor Y, alpha
- CAAT box DNA-binding protein subunit A
- CAAT-box DNA binding protein subunit A
- CCAAT-binding transcription factor subunit B
- HAP2 CCAAT-binding protein
- Transcription factor NF-Y, A subunit
- nuclear transcription factor Y subunit A
- nuclear transcription factor Y subunit alpha
- CAAT-box DNA-binding protein subunit A
- NF-Y protein chain A
- nuclear transcription factor-Y alpha
- NF-YA
- CBF-B
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