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NFAT5 产品

(Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Categories

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured NFAT5 Categories

NFAT5 抗体

High quality antibodies with extensive validation data.

NFAT5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NFAT5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NFAT5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7189436
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948983
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN467533
Quantity 100 μL
Datasheet Datasheet

Recommended NFAT5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593898
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6220090
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6220094
Quantity 96 tests
Datasheet Datasheet

Recommended NFAT5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312438
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NFAT5 Products

Choi, Chaiyamongkol, Doolittle, Johnson, Gogate, Schoepflin, Shapiro, Risbud: "COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells." in: The Journal of biological chemistry, Vol. 293, Issue 23, pp. 8969-8981, (2019) (PubMed).

Rasmussen, Christensen, Holm, Nielsen: "Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells." in: FEBS open bio, Vol. 9, Issue 6, pp. 1071-1081, (2019) (PubMed).

Chen, Cao, Cao, Wang, Xiang, Yang, Ying, Cong: "Protective effect of dexmedetomidine against diabetic hyperglycemia-exacerbated cerebral ischemia/reperfusion injury: An in vivo and in vitro study." in: Life sciences, Vol. 235, pp. 116553, (2019) (PubMed).

Choi, Madhu, Shapiro, Risbud: "Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation." in: Scientific reports, Vol. 9, Issue 1, pp. 15469, (2019) (PubMed).

Hollborn, Fischer, Kuhrt, Wiedemann, Bringmann, Kohen: "Osmotic regulation of NFAT5 expression in RPE cells: The involvement of purinergic receptor signaling." in: Molecular vision, Vol. 23, pp. 116-130, (2017) (PubMed).

Johnson, Shapiro, Risbud: "RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?" in: The Journal of biological chemistry, Vol. 291, Issue 52, pp. 26686-26697, (2016) (PubMed).

Bire, Casteret, Piégu, Beauclair, Moiré, Arensbuger, Bigot: "Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2." in: PLoS genetics, Vol. 12, Issue 3, pp. e1005902, (2016) (PubMed).

Synonyms and alternative names related to NFAT5

nuclear factor of activated T-cells 5 (NFAT5), nuclear factor of activated T-cells 5, tonicity-responsive a (nfat5a), nuclear factor of activated T-cells 5, tonicity-responsive S homeolog (nfat5.S), nuclear factor of activated T-cells 5, tonicity-responsive (nfat5), nuclear factor of activated T-cells 5 (nfat5), nuclear factor of activated T cells 5 (Nfat5), nuclear factor of activated T-cells 5 (Nfat5), AI225870, B130038B15Rik, CAG-8, CAG80, DKFZp469P1514, mKIAA0827, nf-at5, NF-AT5, Nfat, NFAT5, nfatl1, NFATL1, nfatz, NFATZ, orebp, OREBP, TonEBP, tonebp, TONEBP, wu:fi46f11, zgc:63502

Protein level used designations for NFAT5

  • nuclear factor of activated T-cells 5
  • nuclear factor of activated T-cells 5, tonicity-responsive
  • nuclear factor of activated T-cells 5-like
  • NF-AT5
  • T-cell transcription factor NFAT5
  • rel domain-containing transcription factor NFAT5
  • tonicity-responsive enhancer binding protein
  • NFAT-like protein 1
  • TonE-binding protein
  • glutamine rich protein H65
  • osmotic response element-binding protein
  • tonicity-responsive enhancer-binding protein
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