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Neuropeptide Y Receptor 1 抗体

(Neuropeptide Y Receptor 1 (NPY1R))
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. [provided by RefSeq, Nov 2009].

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Featured Neuropeptide Y Receptor 1 Categories

Neuropeptide Y Receptor 1 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our Neuropeptide Y Receptor 1 Products

Dubois, Ramamoorthy, Whim, Liu: "Activation of NPY type 5 receptors induces a long-lasting increase in spontaneous GABA release from cerebellar inhibitory interneurons." in: Journal of neurophysiology, Vol. 107, Issue 6, pp. 1655-65, (2012) (PubMed).

Klenke, Constantin, Wray: "Neuropeptide Y directly inhibits neuronal activity in a subpopulation of gonadotropin-releasing hormone-1 neurons via Y1 receptors." in: Endocrinology, Vol. 151, Issue 6, pp. 2736-46, (2010) (PubMed).

Killough, Lundy, Irwin: "Dental pulp fibroblasts express neuropeptide Y Y1 receptor but not neuropeptide Y." in: International endodontic journal, Vol. 43, Issue 10, pp. 835-42, (2010) (PubMed).

Dailey, Bartness: "Arcuate nucleus destruction does not block food deprivation-induced increases in food foraging and hoarding." in: Brain research, Vol. 1323, pp. 94-108, (2010) (PubMed).

Decressac, Prestoz, Veran, Cantereau, Jaber, Gaillard: "Neuropeptide Y stimulates proliferation, migration and differentiation of neural precursors from the subventricular zone in adult mice." in: Neurobiology of disease, Vol. 34, Issue 3, pp. 441-9, (2009) (PubMed).

El Karim, Lamey, Linden, Lundy: "Neuropeptide Y Y1 receptor in human dental pulp cells of noncarious and carious teeth." in: International endodontic journal, Vol. 41, Issue 10, pp. 850-5, (2008) (PubMed).

Gibbs, Diogenes, Hargreaves: "Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors." in: British journal of pharmacology, Vol. 150, Issue 1, pp. 72-9, (2007) (PubMed).

Zhang, Ossipov, Zhang, Lai, Porreca: "Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons." in: Pain, Vol. 129, Issue 1-2, pp. 143-54, (2007) (PubMed).

Dimitrov, DeJoseph, Brownfield, Urban: "Involvement of neuropeptide Y Y1 receptors in the regulation of neuroendocrine corticotropin-releasing hormone neuronal activity." in: Endocrinology, Vol. 148, Issue 8, pp. 3666-73, (2007) (PubMed).

Urban, Leitermann, DeJoseph, Somponpun, Wolak, Sladek: "Influence of dehydration on the expression of neuropeptide Y Y1 receptors in hypothalamic magnocellular neurons." in: Endocrinology, Vol. 147, Issue 9, pp. 4122-31, (2006) (PubMed).

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