Neuregulin 1 产品
(Neuregulin 1 (NRG1))
Categories
The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009].
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Featured Neuregulin 1 Categories
Neuregulin 1 抗体
High quality antibodies with extensive validation data.
Neuregulin 1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Neuregulin 1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Neuregulin 1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ICC, IHC (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN3044035
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC, IHC (p), IHC (fro)
Validations
- (8)
Cat. No.
ABIN3031973
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, ICC, IF
Validations
- (4)
Cat. No.
ABIN6254897
Quantity
100 μL
Datasheet
Datasheet
Recommended Neuregulin 1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6958084
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6958085
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6958086
Quantity
96 tests
Datasheet
Datasheet
Recommended Neuregulin 1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN6964402
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124139
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313023
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our Neuregulin 1 Products
: "Neuregulin‑1 protects cardiac function in septic rats through multiple targets based on endothelial cells." in: International journal of molecular medicine, Vol. 44, Issue 4, pp. 1255-1266, (2020) (PubMed).: "Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin 1." in: Aging, Vol. 12, Issue 17, pp. 17436-17458, (2020) (PubMed).
: "Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 95, pp. 109669, (2019) (PubMed).
: "Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway." in: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1905-1914, (2017) (PubMed).
: "Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation." in: Translational psychiatry, Vol. 7, Issue 3, pp. e1052, (2017) (PubMed).
: "Effects of prolonged antipsychotic administration on neuregulin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect." in: The Journal of toxicological sciences, Vol. 41, Issue 2, pp. 303-9, (2016) (PubMed).
: "Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib." in: Oncogene, Vol. 35, Issue 7, pp. 878-86, (2016) (PubMed).
: "Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress." in: Physiology & behavior, Vol. 154, pp. 145-50, (2015) (PubMed).
: "Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6596-606, (2015) (PubMed).
: "miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells." in: Neural regeneration research, Vol. 9, Issue 8, pp. 828-36, (2014) (PubMed).
Synonyms and alternative names related to Neuregulin 1
neuregulin 1 (Nrg1), neuregulin 1 (NRG1), histidine rich glycoprotein (HRG), neuregulin 1 L homeolog (nrg1.L), neuregulin 1 (nrg1), 6030402G23Rik, ARIA, D230005F13Rik, DKFZp459A1838, GGF, GGF2, GGFII, heregulin, Hgl, HGL, HRG, HRG1, HRGA, HRGalpha, MST131, NDF, NRG-1, NRG1, nrg1-A, pro-neuregulin-1, SMDF, wu:fm70e01Protein level used designations for Neuregulin 1
- heregulin
- pro-neuregulin-1, membrane-bound isoform
- type I neuregulin 1
- type III neuregulin 1
- neuregulin 1
- HRG-alpha
- heregulin-alpha
- MSTP131
- glial growth factor
- heregulin, alpha (45kD, ERBB2 p185-activator)
- neu differentiation factor
- neuregulin 1 type IV beta 1a
- neuregulin 1 type IV beta 3
- pro-NRG1
- sensory and motor neuron derived factor
- neuregulin 1 type III beta 3
- membrane-bound isoform
- neuregulin 1 alpha isoform
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