NEU1 产品
(Sialidase 1 (Lysosomal Sialidase) (NEU1))
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The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008].
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Featured NEU1 Categories
NEU1 抗体
High quality antibodies with extensive validation data.
NEU1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NEU1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NEU1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7438058
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (9)
Cat. No.
ABIN1491548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN1774878
Quantity
100 μg
Datasheet
Datasheet
Recommended NEU1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6973751
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5518637
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN511750
Quantity
96 tests
Datasheet
Datasheet
Recommended NEU1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125087
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312399
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394420
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NEU1 Products
: "Assessment of total sialic acid levels in patients with hyperemesis gravidarum: a preliminary study." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 38, Issue 4, pp. 532-535, (2018) (PubMed).: "Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 310, Issue 10, pp. L940-54, (2017) (PubMed).
: "The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo." in: Glycobiology, Vol. 26, Issue 8, pp. 834-49, (2016) (PubMed).
: "CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718." in: mBio, Vol. 4, Issue 5, pp. e00770-13, (2013) (PubMed).
: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).
: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).
Synonyms and alternative names related to NEU1
neuraminidase 1 (NEU1), neuraminidase 1 (lysosomal sialidase) L homeolog (neu1.L), neuraminidase 1 (neu1), neuraminidase 1 (Neu1), AA407268, AA407316, Aglp, Apl, Bat-7, Bat7, G9, Map-2, MGC81958, NANH, NEU, Neu, Neu-1, SIAL1Protein level used designations for NEU1
- G9 sialidase
- N-acetyl-alpha-neuraminidase 1
- acetylneuraminyl hydrolase
- exo-alpha-sialidase
- lysosomal sialidase
- sialidase-1
- sialidase 1 (lysosomal sialidase)
- neuraminidase
- isotocin
- Isotocin-neurophysin IT 1
- neuraminidase 1
- sialidase-1-like
- HLA-B-associated transcript 7
- sialidase 1
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