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neonatal Fc Receptor 产品

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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Featured neonatal Fc Receptor Categories

neonatal Fc Receptor 抗体

High quality antibodies with extensive validation data.

neonatal Fc Receptor ELISA试剂盒

Reliable ELISA kits for a wide range of species.

neonatal Fc Receptor 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended neonatal Fc Receptor 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, FACS, cELISA, Func
Validations
  • (15)
  • (8)
Cat. No. ABIN1774762
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS, cELISA
Validations
  • (4)
  • (6)
Cat. No. ABIN7539618
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS, cELISA
Validations
  • (6)
  • (6)
Cat. No. ABIN1774763
Quantity 100 μg
Datasheet Datasheet

Recommended neonatal Fc Receptor ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966700
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974784
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955742
Quantity 96 tests
Datasheet Datasheet

Recommended neonatal Fc Receptor 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7274675
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7274677
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7274676
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our neonatal Fc Receptor Products

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Xu, He, Momben-Abolfath, Vertrees, Li, Norton, Struble: "Zika Virus Infection and Antibody Neutralization in FcRn Expressing Placenta and Engineered Cell Lines." in: Vaccines, Vol. 10, Issue 12, (2022) (PubMed).

Gjølberg, Frick, Mester, Foss, Grevys, Høydahl, Jørstad, Schlothauer, Sandlie, Moe, Andersen: "Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life." in: Communications biology, Vol. 5, Issue 1, pp. 832, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Cines, Zaitsev, Rauova, Rux, Stepanova, Krishnaswamy, Sarkar, Kowalska, Zhao, Mast, Blumberg, McCrae, Poncz, Hubbard, Pyzik, Blumberg: "FcRn augments induction of tissue factor activity by IgG-containing immune complexes." in: Blood, Vol. 135, Issue 23, pp. 2085-2093, (2021) (PubMed).

Hubbard, Pyzik, Rath, Kozicky, Sand, Gandhi, Grevys, Foss, Menzies, Glickman, Fiebiger, Roopenian, Sandlie, Andersen, Sly, Baker, Blumberg: "FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity." in: The Journal of experimental medicine, Vol. 217, Issue 10, (2021) (PubMed).

Bern, Nilsen, Ferrarese, Sand, Gjølberg, Lode, Davidson, Camire, Bækkevold, Foss, Grevys, Dalhus, Wilson, Høydahl, Christianson, Roopenian, Schlothauer, Michaelsen, Moe, Lombardi, Pinotti, Sandlie et al.: "An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. ..." in: Science translational medicine, Vol. 12, Issue 565, (2021) (PubMed).

Casulleras, Flores-Costa, Duran-Güell, Alcaraz-Quiles, Sanz, Titos, López-Vicario, Fernández, Horrillo, Costa, de la Grange, Moreau, Arroyo, Clària: "Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis." in: Science translational medicine, Vol. 12, Issue 566, (2021) (PubMed).

Catlin, Mitchell, Potchoiba, OHara, Wang, Zhang, Weinbauer, Bowman: "Placental transfer of 125 iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey." in: Birth defects research, Vol. 112, Issue 1, pp. 105-117, (2020) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Synonyms and alternative names related to neonatal Fc Receptor

Fc fragment of IgG receptor and transporter (FCGRT), Fc fragment of IgG receptor and transporter (Fcgrt), Fc receptor, IgG, alpha chain transporter (Fcgrt), alpha-chain, FCRN, FcRn

Protein level used designations for neonatal Fc Receptor

  • FcRn alpha chain
  • IgG Fc fragment receptor transporter alpha chain
  • IgG receptor FcRn large subunit p51
  • immunoglobulin receptor, intestinal, heavy chain
  • major histocompatibility complex class I-like Fc receptor
  • neonatal Fc receptor
  • neonatal Fc-receptor for Ig
  • IgG transcytosis and recycling receptor
  • MHC class I-related Fc gamma receptor
  • igG receptor FcRn large subunit p51
  • neonatal Fc receptor FcRn
  • Fc receptor
  • Fc fragment immunoglobulin G receptor
  • Fc receptor, IgG, alpha chain transporter
  • igG Fc fragment receptor transporter alpha chain
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