NEFL 产品
(Neurofilament, Light Polypeptide (NEFL))
Categories
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008].
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Featured NEFL Categories
NEFL 抗体
High quality antibodies with extensive validation data.
NEFL ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NEFL 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NEFL 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN969548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN3020809
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN7268867
Quantity
100 μL
Datasheet
Datasheet
Recommended NEFL ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958109
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6976127
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6958108
Quantity
96 tests
Datasheet
Datasheet
Recommended NEFL 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7092803
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7092809
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124149
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our NEFL Products
: "Serum neurofilament light chain is not a useful biomarker of central nervous system involvement in women with Fabry disease." in: Intractable & rare diseases research, Vol. 10, Issue 4, pp. 276-282, (2021) (PubMed).: "Cytokines and biological markers in autoimmune GFAP astrocytopathy: The potential role for pathogenesis and therapeutic implications." in: Journal of neuroimmunology, Vol. 334, pp. 576999, (2020) (PubMed).
: "RBFOX3/NeuN is dispensable for visual function." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192355, (2018) (PubMed).
: "Staying in the game: a pilot study examining the efficacy of protective headgear in an animal model of mild traumatic brain injury (mTBI)." in: Brain injury, Vol. 31, Issue 11, pp. 1521-1529, (2018) (PubMed).
: "Neurofilament light as an immune target for pathogenic antibodies." in: Immunology, Vol. 152, Issue 4, pp. 580-588, (2017) (PubMed).
: "Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis." in: Frontiers in immunology, Vol. 8, pp. 812, (2017) (PubMed).
: "Effect of carotid endarterectomy on brain damage markers." in: Acta neurologica Scandinavica, (2016) (PubMed).
: "Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study." in: Frontiers in behavioral neuroscience, Vol. 8, pp. 427, (2015) (PubMed).
: "Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle." in: The Journal of reproduction and development, Vol. 61, Issue 3, pp. 229-36, (2015) (PubMed).
: "RBFOX3/NeuN is Required for Hippocampal Circuit Balance and Function." in: Scientific reports, Vol. 5, pp. 17383, (2015) (PubMed).
Synonyms and alternative names related to NEFL
neurofilament light (NEFL), neurofilament, light polypeptide (NEFL), neurofilament, light polypeptide b (neflb), neurofilament, light polypeptide (Nefl), neurofilament light (Nefl), neurofilament, light L homeolog (nefl.L), AI847934, CMT1F, CMT2E, NEFL, nefl, NF-L, NF68, Nfl, NFL, XNF-L, zgc:136626Protein level used designations for NEFL
- neurofilament, light polypeptide 68kDa
- neurofilament, light polypeptide
- neurofilament light polypeptide
- 68 kDa neurofilament protein
- neurofilament protein L
- neurofilament triplet L protein
- light molecular weight neurofilament protein
- neurofilament protein, light chain
- neurofilament subunit NF-L
- NF-L
- micro glutamic acid-rich protein
- neurofilament protein
- Neurofilament triplet L protein
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