NEDD4-2 抗体
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
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NEDD4-2 抗体 by 应用范围
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NEDD4-2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal NEDD4-2 抗体. Click on a link to go to the corresponding products.
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Popular NEDD4-2 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Application
ELISA, WB, IP
Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN6144504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN7264127
Quantity
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Datasheet
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Application
ELISA, WB, IF
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Cat. No.
ABIN7151078
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC
Validations
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Cat. No.
ABIN7237525
Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
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Cat. No.
ABIN7266883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
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- (2)
Cat. No.
ABIN2774731
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, WB
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Cat. No.
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Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
- (1)
Cat. No.
ABIN525092
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis
Application
WB
Validations
- (1)
Cat. No.
ABIN6743164
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Pig, Rabbit
Application
WB, IHC, IP, IF, IHC (p)
Validations
- (1)
Cat. No.
ABIN2625989
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application
WB, IHC, IP, IF, IHC (p)
Validations
- (1)
Cat. No.
ABIN2625990
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ICC
Validations
- (2)
Cat. No.
ABIN2690521
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN744248
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our NEDD4-2 抗体
: "Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1157-65, (2008) (PubMed).Aliases for NEDD4-2 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L) 抗体NEDD4L (LOC776799) 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S) 抗体
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l) 抗体
neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l) 抗体
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