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NCOA3 产品

(Nuclear Receptor Coactivator 3 (NCOA3))
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010].

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Featured NCOA3 Categories

NCOA3 抗体

High quality antibodies with extensive validation data.

NCOA3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NCOA3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCOA3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (5)
Cat. No. ABIN7441217
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7074886
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN3187987
Quantity 100 μL
Datasheet Datasheet

Recommended NCOA3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958248
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958249
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657459
Quantity 96 tests
Datasheet Datasheet

Recommended NCOA3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312128
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407163
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407166
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NCOA3 Products

Zhou, Wei, Chen, Dong, Lai, Fang, Jiang, Lu, Zhou, Xie, Luo, Chen: "Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples." in: Oncotarget, Vol. 7, Issue 27, pp. 41703-41714, (2016) (PubMed).

Battistella, Romero, Castro-Vega, Gapihan, Bouhidel, Bagot, Feugeas, Janin: "The High Expression of the microRNA 17-92 Cluster and its Paralogs, and the Downregulation of the Target Gene PTEN, Is Associated with Primary Cutaneous B-Cell Lymphoma Progression." in: The Journal of investigative dermatology, Vol. 135, Issue 6, pp. 1659-67, (2015) (PubMed).

Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: "Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 21, pp. 5983-91, (2012) (PubMed).

Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: "Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation." in: Cancer research, Vol. 70, Issue 16, pp. 6477-85, (2010) (PubMed).

Kovanen, Saarikoski, Haukka, Pirkola, Aromaa, Lönnqvist, Partonen: "Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption." in: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 45, Issue 4, pp. 303-11, (2010) (PubMed).

Karmakar, Gao, Pace, Oesterreich, Smith: "Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 6, pp. 1187-202, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Lanz, Bulynko, Malovannaya, Labhart, Wang, Li, Qin, Harper, OMalley: "Global characterization of transcriptional impact of the SRC-3 coregulator." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 4, pp. 859-72, (2010) (PubMed).

Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: "Androgen modulation of coregulator expression in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).

Harigopal, Heymann, Ghosh, Anagnostou, Camp, Rimm: "Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome." in: Breast cancer research and treatment, Vol. 115, Issue 1, pp. 77-85, (2009) (PubMed).

Synonyms and alternative names related to NCOA3

nuclear receptor coactivator 3 (NCOA3), nuclear receptor coactivator 3 (Ncoa3), nuclear receptor coactivator 3 S homeolog (ncoa3.S), 2010305B15Rik, ACTR, Actr, actr, AIB-1, aib-1, AIB1, Aib1, aib1, AW321064, bHLHe42, CAGH16, cagh16, CTG26, ctg26, KAT13B, kat13b, NCOA3, p/Cip, pCIP, pCip, pcip, RAC3, Rac3, rac3, SRC-3, src-3, SRC3, Src3, src3, TNRC14, tnrc14, TNRC16, tnrc16, TRAM-1, Tram-1, tram-1, Tram1, xSRC-3

Protein level used designations for NCOA3

  • nuclear receptor coactivator 3
  • CBP-interacting protein
  • amplified in breast cancer 1 protein
  • class E basic helix-loop-helix protein 42
  • receptor-associated coactivator 3
  • steroid receptor coactivator protein 3
  • thyroid hormone receptor activator molecule 1
  • steroid receptor coactivator 3
  • AIB-1
  • NCoA-3
  • RAC-3
  • SRC-3
  • amplified in breast cancer-1 protein homolog
  • retinoid X receptor-interacting coactivator xSRC-3
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