NCK Adaptor Protein 2 产品
(NCK Adaptor Protein 2 (NCK2))
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This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured NCK Adaptor Protein 2 Categories
NCK Adaptor Protein 2 抗体
High quality antibodies with extensive validation data.
NCK Adaptor Protein 2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCK Adaptor Protein 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7074783
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7149353
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN521900
Quantity
50 μg
Datasheet
Datasheet
Recommended NCK Adaptor Protein 2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124118
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312107
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312109
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our NCK Adaptor Protein 2 Products
: "Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis." in: Diabetes, Vol. 65, Issue 9, pp. 2652-66, (2016) (PubMed).: "Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation." in: Cell communication and signaling : CCS, Vol. 12, pp. 21, (2014) (PubMed).
: "The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains." in: The Journal of biological chemistry, Vol. 281, Issue 26, pp. 18236-45, (2006) (PubMed).
: "Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26633-44, (2006) (PubMed).
: "The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network." in: Molecular and cellular biology, Vol. 23, Issue 13, pp. 4586-97, (2003) (PubMed).
Synonyms and alternative names related to NCK Adaptor Protein 2
NCK adaptor protein 2 (NCK2), NCK adaptor protein 2 (Nck2), cytoplasmic protein NCK2-like (LOC100227348), non-catalytic region of tyrosine kinase adaptor protein 2 (Nck2), NCK adaptor protein 2a (nck2a), NCK adaptor protein 2b (nck2b), 4833426I10Rik, fd20h08, GRB4, Grb4, im:7147817, Nck-2, NCK2, Nck2, NCKbeta, si:ch211-147g19.3, wu:fd20h08, zgc:55283, zgc:92024Protein level used designations for NCK Adaptor Protein 2
- SH2/SH3 adaptor protein NCK-beta
- cytoplasmic protein NCK2
- growth factor receptor-bound protein 4
- noncatalytic region of tyrosine kinase, beta
- non-catalytic region of tyrosine kinase adaptor protein 2
- NCK adaptor protein 2
- cytoplasmic protein NCK2-like
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