NCBP1 产品
(Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
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The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008].
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Featured NCBP1 Categories
NCBP1 抗体
High quality antibodies with extensive validation data.
NCBP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NCBP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCBP1 抗体
Product
Reactivity
Application
Validations
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Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN518206
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
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- (3)
Cat. No.
ABIN2856327
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
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- (5)
- (1)
Cat. No.
ABIN1881565
Quantity
400 μL
Datasheet
Datasheet
Recommended NCBP1 ELISA试剂盒
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Reactivity
Analytical Method
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Cat. No.
Quantity
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Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648123
Quantity
96 tests
Datasheet
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Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1145340
Quantity
96 tests
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Recommended NCBP1 蛋白
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Reactivity
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Human
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Wheat germ
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- (1)
Cat. No.
ABIN1312082
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312080
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094046
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NCBP1 Products
: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).: "UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps." in: Molecular cell, Vol. 39, Issue 3, pp. 396-409, (2010) (PubMed).
: "A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation." in: Genes & development, Vol. 23, Issue 17, pp. 2033-45, (2009) (PubMed).
: "The molecular basis for the regulation of the cap-binding complex by the importins." in: Nature structural & molecular biology, Vol. 16, Issue 9, pp. 930-7, (2009) (PubMed).
: "Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex." in: Journal of molecular biology, Vol. 385, Issue 2, pp. 618-27, (2009) (PubMed).
: "SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs." in: Cell, Vol. 133, Issue 2, pp. 303-13, (2008) (PubMed).
: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." in: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).
Synonyms and alternative names related to NCBP1
cap binding protein 80 (Cbp80), nuclear cap binding protein subunit 1 (ncbp1), nuclear cap binding protein subunit 1 S homeolog (ncbp1.S), nuclear cap binding protein subunit 1 (NCBP1), nuclear cap binding protein subunit 1, 80kDa (ncbp1), nuclear cap binding protein subunit 1, 80kDa (NCBP1), nuclear cap binding protein subunit 1 (Ncbp1), nuclear cap binding protein subunit 1 L homeolog (ncbp1.L), ARM repeat superfamily protein (ABH1), Nuclear cap-binding protein subunit 1-A (nbp1a), Nuclear cap-binding protein subunit 1 (ncbp-1), ABA HYPERSENSITIVE 1, ATCBP80, AU014645, AW538051, CAP-BINDING PROTEIN 80, CBP80, cbp80, CG7035, Dmel\\CG7035, EG:84H4.3, ENS, ENSALADA, ncbp, NCBP, ncbp1, NUCLEAR CAP-BINDING PROTEIN CBP80, sto1, Sto1, T10F5.8, T10F5_8Protein level used designations for NCBP1
- CG7035-PA
- CG7035-PB
- CG7035-PC
- Cap-binding protein 80
- Cbp80-PA
- Cbp80-PB
- Cbp80-PC
- nuclear cap-binding protein subunit 1
- CBP80
- NCBP 80 kDa subunit
- 80 kDa nuclear cap-binding protein
- nuclear cap-binding protein subunit 1-B
- nuclear cap binding protein subunit 1, 80kDa
- nuclear cap-binding protein subunit 1-like
- nuclear cap-binding protein subunit 1-A
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