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NCBP1 产品

(Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

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The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008].

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Featured NCBP1 Categories

NCBP1 抗体

High quality antibodies with extensive validation data.

NCBP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NCBP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCBP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN518206
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2856327
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881565
Quantity 400 μL
Datasheet Datasheet

Recommended NCBP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648123
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1145340
Quantity 96 tests
Datasheet Datasheet

Recommended NCBP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312082
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312080
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094046
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NCBP1 Products

Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

Hwang, Sato, Tang, Matsuda, Maquat: "UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps." in: Molecular cell, Vol. 39, Issue 3, pp. 396-409, (2010) (PubMed).

Kim, Cho, Choi, Kim, Kim, Ko, Jang, Kim: "A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation." in: Genes & development, Vol. 23, Issue 17, pp. 2033-45, (2009) (PubMed).

Dias, Wilson, Rojas, Ambrosio, Cerione: "The molecular basis for the regulation of the cap-binding complex by the importins." in: Nature structural & molecular biology, Vol. 16, Issue 9, pp. 930-7, (2009) (PubMed).

Worch, Jankowska-Anyszka, Niedzwiecka, Stepinski, Mazza, Darzynkiewicz, Cusack, Stolarski: "Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex." in: Journal of molecular biology, Vol. 385, Issue 2, pp. 618-27, (2009) (PubMed).

Ma, Yoon, Richardson, Jülich, Blenis: "SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs." in: Cell, Vol. 133, Issue 2, pp. 303-13, (2008) (PubMed).

Hosoda, Kim, Lejeune, Maquat: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." in: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).

Synonyms and alternative names related to NCBP1

cap binding protein 80 (Cbp80), nuclear cap binding protein subunit 1 (ncbp1), nuclear cap binding protein subunit 1 S homeolog (ncbp1.S), nuclear cap binding protein subunit 1 (NCBP1), nuclear cap binding protein subunit 1, 80kDa (ncbp1), nuclear cap binding protein subunit 1, 80kDa (NCBP1), nuclear cap binding protein subunit 1 (Ncbp1), nuclear cap binding protein subunit 1 L homeolog (ncbp1.L), ARM repeat superfamily protein (ABH1), Nuclear cap-binding protein subunit 1-A (nbp1a), Nuclear cap-binding protein subunit 1 (ncbp-1), ABA HYPERSENSITIVE 1, ATCBP80, AU014645, AW538051, CAP-BINDING PROTEIN 80, CBP80, cbp80, CG7035, Dmel\\CG7035, EG:84H4.3, ENS, ENSALADA, ncbp, NCBP, ncbp1, NUCLEAR CAP-BINDING PROTEIN CBP80, sto1, Sto1, T10F5.8, T10F5_8

Protein level used designations for NCBP1

  • CG7035-PA
  • CG7035-PB
  • CG7035-PC
  • Cap-binding protein 80
  • Cbp80-PA
  • Cbp80-PB
  • Cbp80-PC
  • nuclear cap-binding protein subunit 1
  • CBP80
  • NCBP 80 kDa subunit
  • 80 kDa nuclear cap-binding protein
  • nuclear cap-binding protein subunit 1-B
  • nuclear cap binding protein subunit 1, 80kDa
  • nuclear cap-binding protein subunit 1-like
  • nuclear cap-binding protein subunit 1-A
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