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NBPF3 产品

(Neuroblastoma Breakpoint Family, Member 3 (NBPF3))

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This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Feb 2013].

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NBPF3 抗体

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to NBPF3

NBPF member 3 (NBPF3), AE2

Protein level used designations for NBPF3

  • neuroblastoma breakpoint family member 3
  • protein SHIIIa4
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