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N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体

(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
ASAH1 抗体  (AA 144-395) ASAH1 抗体  (AA 144-395) ASAH1 抗体 (AA 144-395) (ABIN7434806)

ASAH1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

ASAH1 抗体  (AA 25-124) ASAH1 抗体  (AA 25-124) ASAH1 抗体 (AA 25-124) (ABIN513533)

ASAH1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated

ASAH1 抗体  (AA 146-395) ASAH1 抗体  (AA 146-395) ASAH1 抗体 (AA 146-395) (ABIN7142987)

ASAH1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

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Find N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体 for a variety of species such as anti-Human N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1, anti-Mouse N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1, anti-Rat N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Popular N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434806
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN513533
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7142987
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN790452
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (4)
Cat. No. ABIN782337
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7142988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7142986
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN513532
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2617268
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6137159
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN2787375
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN783822
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
Cat. No. ABIN1714104
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1700602
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2809965
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体

Cho, Lee, Liu, Wang, Kwon: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." in: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).

Tan, Liu, Fox, Barth, Sharma, Turner, Awwad, Dewey, Doi, Spitzer, Shah, Morad, Desai, Amin, Zhu, Liao, Yun, Kester, Claxton, Wang, Cabot, Schuchman, Levine, Feith, Loughran: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).

Elamin, Titz, Dijon, Merg, Geertz, Schneider, Martin, Schlage, Frentzel, Talamo, Phillips, Veljkovic, Ivanov, Vanscheeuwijck, Peitsch, Hoeng: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).

Cai, Lucki, Sewer: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).

Singh, Dharmarajan, Aye, Keelan: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." in: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).

Lucki, Bandyopadhyay, Wang, Merrill, Sewer: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).

Lucki, Li, Bandyopadhyay, Wang, Merrill, Sewer: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." in: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).

Lucki, Sewer: "Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19399-409, (2011) (PubMed).

He, Huang, Li, Gong, Schuchman: "Deregulation of sphingolipid metabolism in Alzheimer's disease." in: Neurobiology of aging, Vol. 31, Issue 3, pp. 398-408, (2010) (PubMed).

Lucki, Sewer: "The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 706-13, (2009) (PubMed).

Aliases for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体

N-acylsphingosine amidohydrolase 1 (ASAH1) 抗体
N-acylsphingosine amidohydrolase 1 (Asah1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a) 抗体
Acid ceramidase (asah-1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b) 抗体
2310081N20Rik 抗体
AC 抗体
ACDase 抗体
ASAH 抗体
Asah 抗体
asah1 抗体
ASAH1 抗体
MGC82286 抗体
PHP 抗体
PHP32 抗体
SMAPME 抗体
zgc:66026 抗体
zgc:101637 抗体
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