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NAT1 产品

(N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))

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This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Featured NAT1 Categories

NAT1 抗体

High quality antibodies with extensive validation data.

NAT1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NAT1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NAT1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7436222
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (4)
Cat. No. ABIN7168283
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7144675
Quantity 100 μg
Datasheet Datasheet

Recommended NAT1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958007
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958008
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657141
Quantity 96 tests
Datasheet Datasheet

Recommended NAT1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1311997
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124088
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311999
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NAT1 Products

van Eijl, Zhu, Cupitt, Gierula, Götz, Fritsche, Edwards: "Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling." in: PLoS ONE, Vol. 7, Issue 7, pp. e41721, (2012) (PubMed).

Millner, Doll, Cai, States, Hein: "Phenotype of the most common "slow acetylator" arylamine N-acetyltransferase 1 genetic variant (NAT1*14B) is substrate-dependent." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 198-204, (2011) (PubMed).

Henis-Korenblit, Strumpf, Goldstaub, Kimchi: "A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 20, Issue 2, pp. 496-506, (2000) (PubMed).

Smelt, Upton, Adjaye, Payton, Boukouvala, Johnson, Mardon, Sim: "Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos." in: Human molecular genetics, Vol. 9, Issue 7, pp. 1101-7, (2000) (PubMed).

Yamanaka, Poksay, Arnold, Innerarity: "A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme." in: Genes & development, Vol. 11, Issue 3, pp. 321-33, (1997) (PubMed).

Levy-Strumpf, Deiss, Berissi, Kimchi: "DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death." in: Molecular and cellular biology, Vol. 17, Issue 3, pp. 1615-25, (1997) (PubMed).

Synonyms and alternative names related to NAT1

N-acetyltransferase 1 (NAT1), N-acetyl transferase 1 (Nat1), N-acetyltransferase 1 (Nat1), N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), arylamine N-acetyltransferase 1-like (LOC101095575), N-acetyltransferase 1 (arylamine N-acetyltransferase) (Nat1), AAC1, AT-I, MNAT, Nat, NAT-1, Nat-1, NAT1, NATI

Protein level used designations for NAT1

  • N-acetyltransferase type 1
  • arylamide acetylase 1
  • arylamine N-acetyltransferase 1
  • monomorphic arylamine N-acetyltransferase
  • N(alpha)-acetyltransferase 15, NatA auxiliary subunit
  • N-acetyl transferase 1, liver, blood
  • AT-1
  • N-acetyltransferase (arylamine N-acetyltransferase)
  • N-acetyltransferase 1 (arylamine N-acetyltransferase)
  • NAT-1
  • MNAT
  • Arylamide acetylase 1
  • Monomorphic arylamine N-acetyltransferase
  • NAT1 9
  • acetyltransferase AT-I
  • arylamine acetyltransferase
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