Nanog 产品
(Nanog Homeobox (NANOG))
Categories
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
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Featured Nanog Categories
Nanog 抗体
High quality antibodies with extensive validation data.
Nanog ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Nanog 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Nanog 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC, ICC, IHC (p), IP, IHC (fro)
Validations
- (6)
- (14)
Cat. No.
ABIN2854880
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN2177828
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS, ICC
Validations
- (9)
Cat. No.
ABIN7155816
Quantity
100 μL
Datasheet
Datasheet
Recommended Nanog ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968797
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958029
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative DNA-Binding ELISA
Validations
- (2)
Cat. No.
ABIN5526712
Quantity
96 tests
Datasheet
Datasheet
Recommended Nanog 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667504
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124111
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667930
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Nanog Products
: "Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma." in: Journal of cellular and molecular medicine, (2021) (PubMed).: "SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG." in: Cell death & disease, Vol. 10, Issue 11, pp. 794, (2020) (PubMed).
: "Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 10420, (2019) (PubMed).
: "Direct conversion of mouse embryonic fibroblast to osteoblast cells using hLMP-3 with Yamanaka factors." in: The international journal of biochemistry & cell biology, Vol. 106, pp. 84-95, (2019) (PubMed).
: "Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming." in: Cell discovery, Vol. 5, pp. 11, (2019) (PubMed).
: "Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 7, pp. 876-887, (2019) (PubMed).
: "Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression." in: Biochemical and biophysical research communications, Vol. 509, Issue 4, pp. 1008-1014, (2019) (PubMed).
: "Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection." in: Cell reports, Vol. 26, Issue 12, pp. 3391-3399.e4, (2019) (PubMed).
: "Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging." in: Scientific reports, Vol. 9, Issue 1, pp. 7014, (2019) (PubMed).
: "Resistance of primary breast cancer cells with enhanced pluripotency and stem cell activity to sex hormonal stimulation and suppression." in: The international journal of biochemistry & cell biology, Vol. 105, pp. 84-93, (2019) (PubMed).
Synonyms and alternative names related to Nanog
Nanog homeobox (Nanog), Nanog homeobox (NANOG), nanog homeobox (nanog), 2410002E02Rik, ecat4, ENK, hacp, NANOG, wu:fd19e04, wu:fd20a07, zgc:193933Protein level used designations for Nanog
- ES cell-associated protein 4
- early embryo specific expression NK family
- early embryo specific expression NK-type homeobox protein
- homeobox protein NANOG
- homeobox transcription factor Nanog
- hNanog
- homeobox transcription factor Nanog-delta 48
- homeobox transcription factor NANOG
- Nanog homeobox
- nanog homeobox transcription factor
- homeodomain transcription factor Nanog
- LOW QUALITY PROTEIN: homeobox protein NANOG
- fd20a07
- nanog homeobox
- ovary-expressed homeobox protein
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