Naip5 蛋白
(NLR Family, Apoptosis Inhibitory Protein 5 (NAIP5))
Confers resistance to microbial infection. Participates in the antimicrobial response by sensing flagellin of Legionella or Salmonella and by stimulating CASP1 activation. This favors the fusion of bacteria-containing phagosomes with lysosomes, restricts bacterial replication and releases proinflammatory cytokines that control bacterial infection. Prevents motor-neuron apoptosis induced by a variety of signals.
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Synonyms and alternative names related to Naip5
NLR family, apoptosis inhibitory protein 5 (Naip5), Birc1e, Lgn1, Naip-rs3Protein level used designations for Naip5
- Legionella, susceptiblility 1
- baculoviral IAP repeat-containing 1e
- baculoviral IAP repeat-containing protein 1e
- neuronal apoptosis inhibitory protein 5
- neuronal apoptosis inhibitory protein, related sequence 3
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