NAIP 产品
(NLR Family, Apoptosis Inhibitory Protein (NAIP))
Categories
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length\; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured NAIP Categories
NAIP 抗体
High quality antibodies with extensive validation data.
NAIP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
NAIP 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NAIP 抗体
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Reactivity
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Cat. No.
ABIN7145194
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC
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Cat. No.
ABIN7268931
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100 μL
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Cat. No.
ABIN7442096
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Recommended NAIP ELISA试剂盒
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ABIN6968952
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ABIN6958208
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96 tests
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Recommended NAIP 蛋白
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Wheat germ
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Cat. No.
ABIN1311946
Quantity
10 μg
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Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414174
Quantity
100 μg
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Reactivity
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Escherichia coli (E. coli)
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ABIN7394255
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Latest Publications for our NAIP Products
: "Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections." in: Frontiers in microbiology, Vol. 10, pp. 2020, (2019) (PubMed).: "Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 815-9, (2015) (PubMed).
: "Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin." in: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38460-72, (2012) (PubMed).
: "NAIP and Ipaf control Legionella pneumophila replication in human cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6808-15, (2008) (PubMed).
: "Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40622-8, (2004) (PubMed).
: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." in: Nature, Vol. 426, Issue 6965, pp. 450-4, (2003) (PubMed).
: "The inhibitors of apoptosis: there is more to life than Bcl2." in: Oncogene, Vol. 22, Issue 53, pp. 8568-80, (2003) (PubMed).
: "Angiotensin-converting enzyme 2 is an essential regulator of heart function." in: Nature, Vol. 417, Issue 6891, pp. 822-8, (2002) (PubMed).
: "NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells." in: Leukemia research, Vol. 26, Issue 9, pp. 857-62, (2002) (PubMed).
: "Vascular gp91(phox): beyond the endothelium." in: Circulation research, Vol. 87, Issue 1, pp. 1-3, (2000) (PubMed).
Synonyms and alternative names related to NAIP
NLR family apoptosis inhibitory protein (NAIP), NLR family, apoptosis inhibitory protein 1 (Naip1), AV364616, BIRC1, Birc1a, D13Lsd1, Naip, Naip-rs1, NLRB1, psiNAIPProtein level used designations for NAIP
- baculoviral IAP repeat-containing protein 1
- neuronal apoptosis inhibitory protein
- nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1
- psi neuronal apoptosis inhibitory protein
- baculoviral IAP repeat-containing 1
- baculoviral IAP repeat-containing 1a
- baculoviral IAP repeat-containing protein 1a
- neuronal apoptosis inhibitory protein 1
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