NAGPA 产品
(N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))
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Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network. [provided by RefSeq, Jul 2008].
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Featured NAGPA Categories
Recommended NAGPA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
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Cat. No.
ABIN7160684
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA, WB
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Cat. No.
ABIN565555
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN7160687
Quantity
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Datasheet
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Synonyms and alternative names related to NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA), N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAEGRDRAFT_56913), N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (Nagpa), AI596180, APAA, NAGPA, UCEProtein level used designations for NAGPA
- N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- alpha-N-acetylglucosaminyl phosphodiesterase
- lysosomal alpha-N-acetylglucosaminidase
- mannose 6-phosphate-uncovering enzyme
- phosphodiester alpha-GlcNAcase
- alpha-GlcNAcase
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