NAC1 产品
(Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012].
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Featured NAC1 Categories
Recommended NAC1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN202717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN6243841
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN202718
Quantity
100 μL
Datasheet
Datasheet
Recommended NAC1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3084172
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124212
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NAC1 Products
: "Nucleus accumbens-associated protein-1 promotes glycolysis and survival of hypoxic tumor cells via the HDAC4-HIF-1α axis." in: Oncogene, (2017) (PubMed).: "Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer." in: Oncology letters, Vol. 13, Issue 6, pp. 4713-4719, (2017) (PubMed).
: "Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis." in: PLoS ONE, Vol. 8, Issue 7, pp. e69099, (2013) (PubMed).
: "NAC1, A POZ/BTB protein interacts with Parkin and may contribute to Parkinson's disease." in: Neuroscience, Vol. 257, pp. 86-95, (2013) (PubMed).
: "Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas." in: British journal of cancer, Vol. 107, Issue 2, pp. 300-7, (2012) (PubMed).
: "NAC1, a BTB/POZ protein overexpressed in uterine sarcomas." in: Anticancer research, Vol. 32, Issue 9, pp. 3841-5, (2012) (PubMed).
: "Nucleus Accumbens 1, a Pox virus and Zinc finger/Bric-a-brac Tramtrack Broad protein binds to TAR DNA-binding protein 43 and has a potential role in Amyotrophic Lateral Sclerosis." in: Neuroscience, Vol. 227, pp. 44-54, (2012) (PubMed).
: "Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 24, Issue 5, pp. 638-45, (2011) (PubMed).
: "Cell cycle-dependent alteration in NAC1 nuclear body dynamics and morphology." in: Physical biology, Vol. 8, Issue 1, pp. 15005, (2011) (PubMed).
: "Novel events in the molecular regulation of muscle mass in critically ill patients." in: The Journal of physiology, Vol. 589, Issue Pt 15, pp. 3883-95, (2011) (PubMed).
Synonyms and alternative names related to NAC1
nucleus accumbens associated 1 (NACC1), nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1), nucleus accumbens associated 1 (Nacc1), 2010001H03Rik, 4930511N13Rik, BEND8, BTBD14B, Btbd14b, BTBD30, NAC-1, Nac-1, NAC1, Nac1, NACC1Protein level used designations for NAC1
- BEN domain containing 8
- BTB/POZ domain-containing protein 14B
- nucleus accumbens-associated protein 1
- transcriptional repressor NAC1
- nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
- BTB (POZ) domain containing 14B
- NAC-1
- nucleus accumbens-1
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