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NABP1 / OBFC2A 抗体

(Nucleic Acid Binding Protein 1a (NABP1A))
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) (By similarity). {ECO:0000250}.

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Synonyms and alternative names related to NABP1 / OBFC2A

nucleic acid binding protein 1 (NABP1), nucleic acid binding protein 1a (nabp1a), nabp1, OBFC2A, obfc2a, obfc2aa, SOSS-B2, SSB2, wu:fc60e10, wu:fi33c08, zgc:101644

Protein level used designations for NABP1 / OBFC2A

  • SOSS complex subunit B2
  • nucleic acid-binding protein 1
  • oligonucleotide/oligosaccharide-binding fold containing 2A
  • oligonucleotide/oligosaccharide-binding fold-containing protein 2A
  • sensor of single-strand DNA complex subunit B2
  • sensor of ssDNA subunit B2
  • single-stranded DNA-binding protein 2
  • Nucleic acid-binding protein 1
  • Oligonucleotide/oligosaccharide-binding fold-containing protein 2A
  • SOSS-B2
  • Sensor of single-strand DNA complex subunit B2
  • Sensor of ssDNA subunit B2
  • Single-stranded DNA-binding protein 2
  • fc60e10
  • fi33c08
  • oligonucleotide/oligosaccharide-binding fold containing 2Aa
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