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MYO9B 产品

(Myosin IXB (MYO9B))

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This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin\; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

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Featured MYO9B Categories

MYO9B 抗体

High quality antibodies with extensive validation data.

Recommended MYO9B 抗体

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
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Cat. No. ABIN6257337
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7184482
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
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Cat. No. ABIN185642
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Recommended MYO9B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
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Cat. No. ABIN1311840
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MYO9B Products

McMichael, Scherer, Franklin, Lee: "The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity." in: PLoS ONE, Vol. 9, Issue 1, pp. e87402, (2014) (PubMed).

Monsuur, de Bakker, Alizadeh, Zhernakova, Bevova, Strengman, Franke, vant Slot, van Belzen, Lavrijsen, Diosdado, Daly, Mulder, Mearin, Meijer, Meijer, van Oort, Wapenaar, Koeleman, Wijmenga: "Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect." in: Nature genetics, Vol. 37, Issue 12, pp. 1341-4, (2005) (PubMed).

Synonyms and alternative names related to MYO9B

myosin IXB (MYO9B), myosin IXb (Myo9b), myosin IXb (myo9b), unconventional myosin-IXb (LOC100450445), myosin IXB (Myo9b), CELIAC4, fb53f01, MYO9B, MYR5, si:dkeyp-66d1.8, wu:fb53f01, wu:fc47c07

Protein level used designations for MYO9B

  • myosin-IXb
  • unconventional myosin IXb
  • unconventional myosin-9b
  • unconventional myosin-IXb
  • Unconventional myosin from rat 3
  • myr 5
  • myosin IXB
  • myosin-IXb-like
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