MYO5A 产品
(Myosin VA (MYO5A))
Categories
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008].
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Featured MYO5A Categories
MYO5A 抗体
High quality antibodies with extensive validation data.
MYO5A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MYO5A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MYO5A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7174953
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (4)
Cat. No.
ABIN7264882
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7442708
Quantity
100 μL
Datasheet
Datasheet
Recommended MYO5A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957980
Quantity
96 tests
Datasheet
Datasheet
Recommended MYO5A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311826
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397510
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424266
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MYO5A Products
: "The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity." in: The Journal of investigative dermatology, (2019) (PubMed).: "The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis." in: The Journal of biological chemistry, Vol. 294, Issue 42, pp. 15418-15434, (2019) (PubMed).
: "Myosin Va is required for the transport of fragile X mental retardation protein (FMRP) granules." in: Biology of the cell, Vol. 106, Issue 2, pp. 57-71, (2014) (PubMed).
: "Actin and myosin-dependent localization of mRNA to dendrites." in: PLoS ONE, Vol. 9, Issue 3, pp. e92349, (2014) (PubMed).
: "Myosin Va is required for P body but not stress granule formation." in: The Journal of biological chemistry, Vol. 286, Issue 13, pp. 11519-28, (2011) (PubMed).
: "Myosin Va cooperates with PKA RIalpha to mediate maintenance of the endplate in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 2031-6, (2010) (PubMed).
: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).
: "Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 18, Issue 9, pp. 989-91, (2004) (PubMed).
: "Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)." in: The Journal of clinical investigation, Vol. 112, Issue 3, pp. 450-6, (2003) (PubMed).
: "Interactions of human Myosin Va isoforms, endogenously expressed in human melanocytes, are tightly regulated by the tail domain." in: The Journal of investigative dermatology, Vol. 120, Issue 3, pp. 465-75, (2003) (PubMed).
Synonyms and alternative names related to MYO5A
myosin VA L homeolog (myo5a.L), myosin VAa (myo5aa), myosin VA (MYO5A), myosin va (PY04789), myosin VA (Myo5a), 9630007J19Rik, AI413174, AI661011, D, d, d-120J, Dbv, DILUTE, Dop, flail, flr, GS1, MGC53270, MVa, Myh12, MYH12, Myo5, MYO5, myo5a, MYO5A, MYOA, MyoVA, myoxin), MYR12, non-muscle, Sev-1, si:dkey-266j9.1Protein level used designations for MYO5A
- myosin VA
- heavy polypeptide 12
- myosin VA (heavy polypeptide 12, myoxin)
- myosin-Va
- myoxin
- myosin Va
- myosin va
- dilute myosin heavy chain, non-muscle
- dilute-opisthotonus
- myosin 5a
- unconventional myosin-Va
- dilute lethal-20J protein
- flailer
- myosin 5A
- myosin I heavy chain isoform
- myosin VA (heavy chain 12, myoxin)
- myosin heavy chain P190
- myosin-V
- myosin V
- myosin, heavy polypeptide kinase
- myosin-12
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