MYCN 产品
(N-Myc Proto-Oncogene Protein (MYCN))
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].
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Featured MYCN Categories
MYCN 抗体
High quality antibodies with extensive validation data.
MYCN ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MYCN 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MYCN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
- (1)
Cat. No.
ABIN760676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
Cat. No.
ABIN1680957
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (6)
Cat. No.
ABIN7193585
Quantity
100 μL
Datasheet
Datasheet
Recommended MYCN ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974813
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5591497
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN2870005
Quantity
96 tests
Datasheet
Datasheet
Recommended MYCN 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (4)
- (1)
Cat. No.
ABIN1311728
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124095
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311730
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MYCN Products
: "P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma." in: Molecular & cellular proteomics : MCP, Vol. 22, Issue 3, pp. 100504, (2023) (PubMed).: "SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells." in: Scientific reports, Vol. 6, pp. 31615, (2016) (PubMed).
: "Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease." in: Oncotarget, Vol. 7, Issue 14, pp. 18605-19, (2016) (PubMed).
: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
: "p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma." in: Molecular cancer research : MCR, Vol. 13, Issue 3, pp. 584-91, (2015) (PubMed).
: "Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma." in: Molecular oncology, (2015) (PubMed).
: "Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells." in: The Journal of biological chemistry, Vol. 290, Issue 10, pp. 6106-19, (2015) (PubMed).
: "The role of histone demethylase KDM4B in Myc signaling in neuroblastoma." in: Journal of the National Cancer Institute, Vol. 107, Issue 6, pp. djv080, (2015) (PubMed).
: "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3? resulting in the stabilization of MYCN in human neuroblastomas." in: PLoS genetics, Vol. 10, Issue 1, pp. e1003996, (2014) (PubMed).
: "Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells." in: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 7, pp. 1115-31, (2014) (PubMed).
Synonyms and alternative names related to MYCN
MYCN proto-oncogene, bHLH transcription factor (MYCN), v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn), MYCN proto-oncogene, bHLH transcription factor (Mycn), olfactory receptor 8S1 (LOC515887), MYCN proto-oncogene, bHLH transcription factor (mycn), MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S), bHLHe37, c-nmyc, fb57a02, MODED, mycn, mycn-a, mycn-b, mycna, MYCNOT, N-myc, Nmuc1, NMYC, Nmyc, Nmyc-1, Nmyc1, nmyc1, ODED, wu:fb57a02, XN-myc, xN-myc1, XNmyc, zgc:85706Protein level used designations for MYCN
- N-myc proto-oncogene protein
- class E basic helix-loop-helix protein 37
- neuroblastoma MYC oncogene
- neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
- oncogene NMYC
- pp65/67
- v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
- N-myc protein
- neuroblastoma myc-related oncogene 1
- Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc)
- Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc)
- N-myc-like protein
- v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
- MYCN proto-oncogene, bHLH transcription factor S homeolog
- v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a
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