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MX2 产品

(MX dynamin like GTPase 2 (MX2))

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The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008].

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Featured MX2 Categories

MX2 抗体

High quality antibodies with extensive validation data.

MX2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MX2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MX2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6259565
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7156645
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN518112
Quantity 50 μg
Datasheet Datasheet

Recommended MX2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958001
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657129
Quantity 96 tests
Datasheet Datasheet

Recommended MX2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311682
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409755
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2130696
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MX2 Products

Kane, Rebensburg, Takata, Zang, Yamashita, Kvaratskhelia, Bieniasz: "Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2." in: eLife, Vol. 7, (2019) (PubMed).

Martinez-Lopez, Martin-Fernandez, Buta, Kim, Bogunovic, Diaz-Griffero: "SAMHD1 deficient human monocytes autonomously trigger type I interferon." in: Molecular immunology, Vol. 101, pp. 450-460, (2019) (PubMed).

Yi, An, Liu, Xu, Raniga, Li, Zhou, Wang, Zhang, Zhou, Zhang, An, Qin, Guo, Li, Liang, Cen: "Human MxB Inhibits the Replication of Hepatitis C Virus." in: Journal of virology, Vol. 93, Issue 1, (2019) (PubMed).

Opp, Vieira, Schulte, Chanda, Diaz-Griffero: "MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells." in: Journal of virology, Vol. 90, Issue 6, pp. 3056-64, (2016) (PubMed).

Wei, Guo, Ma, Markham, Yu: "Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations." in: EBioMedicine, Vol. 8, pp. 230-6, (2016) (PubMed).

Sali, Pryke, Abraham, Liu, Archer, Broeckel, Staverosky, Smith, Al-Shammari, Amsler, Sheridan, Nilsen, Streblow, DeFilippis: "Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses." in: PLoS pathogens, Vol. 11, Issue 12, pp. e1005324, (2015) (PubMed).

Sandler, Bosinger, Estes, Zhu, Tharp, Boritz, Levin, Wijeyesinghe, Makamdop, del Prete, Hill, Timmer, Reiss, Yarden, Darko, Contijoch, Todd, Silvestri, Nason, Norgren, Keele, Rao, Langer, Lifson et al.: "Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. ..." in: Nature, Vol. 511, Issue 7511, pp. 601-5, (2014) (PubMed).

Kane, Yadav, Bitzegeio, Kutluay, Zang, Wilson, Schoggins, Rice, Yamashita, Hatziioannou, Bieniasz: "MX2 is an interferon-induced inhibitor of HIV-1 infection." in: Nature, Vol. 502, Issue 7472, pp. 563-6, (2013) (PubMed).

Synonyms and alternative names related to MX2

MX dynamin-like GTPase 2 (Mx2), MX dynamin like GTPase 2 (Mx2), MX dynamin like GTPase 2 (MX2), myxovirus (influenza virus) resistance 2 (mouse) (MX2), AI528743, Mx-2, Mx3, MXB

Protein level used designations for MX2

  • interferon-induced GTP-binding protein Mx2
  • myxovirus resistance protein 2
  • interferon-induced GTP-binding protein Mx3
  • myxovirus (influenza virus) resistance 3
  • myxovirus resistance protein 3
  • interferon-regulated resistance GTP-binding protein MXB
  • p78-related protein
  • second interferon-induced protein p78
  • Mx protein
  • myxovirus (influenza virus) resistance 2 , interferon-inducible protein p78
  • GTP-binding protein Mx2
  • myxovirus resistance 2
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