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Muscarinic Acetylcholine Receptor M2 产品

(Cholinergic Receptor, Muscarinic 2 (CHRM2))

Categories

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured Muscarinic Acetylcholine Receptor M2 Categories

Muscarinic Acetylcholine Receptor M2 抗体

High quality antibodies with extensive validation data.

Muscarinic Acetylcholine Receptor M2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Muscarinic Acetylcholine Receptor M2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Muscarinic Acetylcholine Receptor M2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), FACS
Validations
  • (5)
Cat. No. ABIN6242476
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7266346
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), FACS, ICC, IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN668646
Quantity 100 μL
Datasheet Datasheet

Recommended Muscarinic Acetylcholine Receptor M2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965798
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965797
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965796
Quantity 96 tests
Datasheet Datasheet

Recommended Muscarinic Acetylcholine Receptor M2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349388
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7491491
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393448
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Muscarinic Acetylcholine Receptor M2 Products

Iguchi, Malykhina, Wilcox: "Early life voiding dysfunction leads to lower urinary tract dysfunction through alteration of muscarinic and purinergic signaling in the bladder." in: American journal of physiology. Renal physiology, Vol. 315, Issue 5, pp. F1320-F1328, (2018) (PubMed).

Ishizuka, Ozawa, Katsuura, Nomura, Satoh: "Effects of muscarinic acetylcholine receptor stimulation on the differentiation of mouse induced pluripotent stem cells into neural progenitor cells." in: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 11, pp. 1198-1205, (2018) (PubMed).

Bastian, Gordon, Jackson: "A novel cell-based assay for inhibitory anti-muscarinic type 3 receptor antibodies in primary Sjögren's syndrome." in: Journal of immunological methods, Vol. 427, pp. 117-21, (2015) (PubMed).

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).

Hendershot, Bryan, Ewing, Claus, Hutchison: "Preliminary evidence for associations of CHRM2 with substance use and disinhibition in adolescence." in: Journal of abnormal child psychology, Vol. 39, Issue 5, pp. 671-81, (2011) (PubMed).

Strang, Renna, Amthor, Keyser: "Muscarinic acetylcholine receptor localization and activation effects on ganglion response properties." in: Investigative ophthalmology & visual science, Vol. 51, Issue 5, pp. 2778-89, (2010) (PubMed).

Monaco, Zanusso, Mazzucco, Rizzuto: "Cerebral amyloidoses: molecular pathways and therapeutic challenges." in: Current medicinal chemistry, Vol. 13, Issue 16, pp. 1903-13, (2006) (PubMed).

Gosso, van Belzen, de Geus, Polderman, Heutink, Boomsma, Posthuma: "Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families." in: Genes, brain, and behavior, Vol. 5, Issue 8, pp. 577-84, (2006) (PubMed).

Luo, Kranzler, Zuo, Wang, Blumberg, Gelernter: "CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study." in: Human molecular genetics, Vol. 14, Issue 16, pp. 2421-34, (2005) (PubMed).

Wang, Hinrichs, Stock, Budde, Allen, Bertelsen, Kwon, Wu, Dick, Rice, Jones, Nurnberger, Tischfield, Porjesz, Edenberg, Hesselbrock, Crowe, Schuckit, Begleiter, Reich, Goate, Bierut: "Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome." in: Human molecular genetics, Vol. 13, Issue 17, pp. 1903-11, (2004) (PubMed).

Synonyms and alternative names related to Muscarinic Acetylcholine Receptor M2

cholinergic receptor muscarinic 2 (CHRM2), cholinergic receptor, muscarinic 2, cardiac (Chrm2), cholinergic receptor, muscarinic 2a (chrm2a), cholinergic receptor, muscarinic 2 (Chrm2), cholinergic receptor muscarinic 2 (Chrm2), AChR-M2, Acm2, Chrm-2, chrm2, GPM2, HM2, M2

Protein level used designations for Muscarinic Acetylcholine Receptor M2

  • 7TM receptor
  • acetylcholine receptor, muscarinic 2
  • muscarinic M2 receptor
  • muscarinic acetylcholine receptor M2
  • AChR M2
  • muscarinic acetylcholine receptor 2
  • cholinergic receptor, muscarinic 2
  • cardiac muscarinic acetylcholine receptor
  • muscarinic acetylcholine receptor m2
  • m2 muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor M2
  • cholinergic receptor muscarinic 2
  • muscarinic acetylcholine receptor M2-like
  • M2 muscarinic acetylcholine receptor
  • cholinergic receptor, muscarinic 2, cardiac
  • muscarinic receptor m2
  • muscarinic receptor 2
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