MUC5B 产品
(Mucin 5 Subtype B (MUC5B))
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This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010].
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Featured MUC5B Categories
MUC5B 抗体
High quality antibodies with extensive validation data.
MUC5B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MUC5B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MUC5B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7429016
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS, Neut
Validations
- (5)
Cat. No.
ABIN7193318
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193568
Quantity
100 μL
Datasheet
Datasheet
Recommended MUC5B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957907
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6957906
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957908
Quantity
96 tests
Datasheet
Datasheet
Recommended MUC5B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311644
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7505621
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7411138
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MUC5B Products
: "Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions." in: Innate immunity, Vol. 27, Issue 1, pp. 89-98, (2022) (PubMed).: "ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism." in: Mucosal immunology, Vol. 12, Issue 5, pp. 1092-1103, (2020) (PubMed).
: "Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model." in: Nutrients, Vol. 11, Issue 10, (2019) (PubMed).
: "Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps." in: Allergy, Vol. 74, Issue 1, pp. 131-140, (2019) (PubMed).
: "Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease." in: International archives of allergy and immunology, Vol. 176, Issue 1, pp. 15-25, (2018) (PubMed).
: "Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling." in: European journal of pharmacology, Vol. 824, pp. 30-39, (2018) (PubMed).
: "Effect of Inhaled Corticosteroids on Salival Composition: A Cross-Sectional Study in Patients with Bronchial Asthma." in: Clinical drug investigation, Vol. 35, Issue 9, pp. 569-74, (2015) (PubMed).
: "Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 6, pp. 657-665, (2015) (PubMed).
: "Secreted mucins and airway bacterial colonization in non-CF bronchiectasis." in: Respirology (Carlton, Vic.), Vol. 20, Issue 7, pp. 1082-8, (2015) (PubMed).
: "New candidate biomarkers in the female genital tract to evaluate microbicide toxicity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110980, (2014) (PubMed).
Synonyms and alternative names related to MUC5B
mucin 5B, oligomeric mucus/gel-forming (MUC5B), mucin 5B, oligomeric mucus/gel-forming (Muc5b), ovomucin, alpha subunit (LOC395381), mucin 5AC, oligomeric mucus/gel-forming (MUC5AC), mucin 5B, oligomeric mucus/gel-forming (muc5b), mucin-5B (LOC100498539), mucin 5, subtype B, tracheobronchial (Muc5b), 2300002I04Rik, A130042M24, AV085033, MG1, MUC-5B, MUC5, MUC5B, MUC9, mucin 5b, RGD1561983Protein level used designations for MUC5B
- cervical mucin MUC5B
- high molecular weight salivary mucin MG1
- mucin 5, subtype B, tracheobronchial
- mucin-5B
- sublingual gland mucin
- ovomucin
- ovomucin, alpha-subunit
- mucin 5B, oligomeric mucus/gel-forming
- mucin protein
- mucin 5, subtype B, tracheobronchial-like
- mucin-5B-like
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