MUC1 抗体
(Mucin 1 (MUC1))
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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Cat. No.
ABIN6940113
Quantity
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Datasheet
Datasheet
Reactivity
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Application
IHC (p), IHC (fro)
Validations
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Cat. No.
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Quantity
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Datasheet
Reactivity
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Application
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Quantity
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Datasheet
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Latest Publications for our MUC1 抗体
: "A three-dimensional A549 cell culture model to study respiratory syncytial virus infections." in: Journal of infection and public health, Vol. 13, Issue 8, pp. 1142-1147, (2020) (PubMed).: "Expression of cyclooxygenase-2 and mucin 1 in colorectal cancer." in: Molecular and clinical oncology, Vol. 13, Issue 5, pp. 52, (2020) (PubMed).
: "MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway." in: Journal of cellular physiology, (2019) (PubMed).
: "MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease." in: Respiratory research, Vol. 19, Issue 1, pp. 226, (2019) (PubMed).
: "Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7." in: International immunopharmacology, Vol. 58, pp. 64-71, (2018) (PubMed).
: "miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor." in: Scientific reports, Vol. 6, pp. 27914, (2018) (PubMed).
: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).
: "Effect of cyclooxygenase‑2 inhibition on the development of post‑traumatic stress disorder in rats." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 4925-4932, (2018) (PubMed).
: "Acetylpuerarin protects against OGD-induced cell injury in BV2 microglia by inhibiting HMGB1 release." in: Die Pharmazie, Vol. 73, Issue 2, pp. 92-97, (2018) (PubMed).
: "Effects of oral cimetidine on the reproductive system of male rats." in: Experimental and therapeutic medicine, Vol. 15, Issue 6, pp. 4643-4650, (2018) (PubMed).
Aliases for MUC1 抗体
mucin 1, cell surface associated (MUC1) 抗体mucin 1, cell surface associated (Muc1) 抗体
mucin 1, transmembrane (Muc1) 抗体
CA 15-3 抗体
CD227 抗体
EMA 抗体
H23AG 抗体
KL-6 抗体
MAM6 抗体
MCKD1 抗体
MUC-1 抗体
Muc-1 抗体
MUC-1/SEC 抗体
MUC-1/X 抗体
MUC1/ZD 抗体
PEM 抗体
PEMT 抗体
PUM 抗体
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