MUC1 产品
(Mucin 1 (MUC1))
Categories
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].
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Featured MUC1 Categories
MUC1 抗体
High quality antibodies with extensive validation data.
MUC1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MUC1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MUC1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
IHC, WB, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440383
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
IHC, WB, IP, ICC
Validations
- (8)
Cat. No.
ABIN7442027
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (8)
Cat. No.
ABIN6940099
Quantity
100 μg
Datasheet
Datasheet
Recommended MUC1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (5)
Cat. No.
ABIN6730894
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968677
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968678
Quantity
96 tests
Datasheet
Datasheet
Recommended MUC1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275298
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1311631
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7013439
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MUC1 Products
: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).: "A three-dimensional A549 cell culture model to study respiratory syncytial virus infections." in: Journal of infection and public health, Vol. 13, Issue 8, pp. 1142-1147, (2020) (PubMed).
: "Expression of cyclooxygenase-2 and mucin 1 in colorectal cancer." in: Molecular and clinical oncology, Vol. 13, Issue 5, pp. 52, (2020) (PubMed).
: "MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway." in: Journal of cellular physiology, (2019) (PubMed).
: "MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease." in: Respiratory research, Vol. 19, Issue 1, pp. 226, (2019) (PubMed).
: "An adherent mucus layer attenuates the genotoxic effect of colibactin." in: Cellular microbiology, Vol. 20, Issue 2, (2018) (PubMed).
: "Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7." in: International immunopharmacology, Vol. 58, pp. 64-71, (2018) (PubMed).
: "miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor." in: Scientific reports, Vol. 6, pp. 27914, (2018) (PubMed).
: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).
: "Effect of cyclooxygenase‑2 inhibition on the development of post‑traumatic stress disorder in rats." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 4925-4932, (2018) (PubMed).
Synonyms and alternative names related to MUC1
mucin 1, cell surface associated (MUC1), mucin 1, cell surface associated (Muc1), mucin 1, transmembrane (Muc1), CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUMProtein level used designations for MUC1
- DF3 antigen
- H23 antigen
- breast carcinoma-associated antigen DF3
- cancer antigen 15-3
- carcinoma-associated mucin
- episialin
- krebs von den Lungen-6
- mucin 1, transmembrane
- mucin-1
- peanut-reactive urinary mucin
- polymorphic epithelial mucin
- tumor associated epithelial mucin
- tumor-associated epithelial membrane antigen
- tumor-associated mucin
- endometrial mucin-1
- epithelial mucin
- MUC-1
- Mucin1
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