MTA1 抗体
(Metastasis Associated 1 (MTA1))
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
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MTA1 抗体 by Grade
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MTA1 抗体 by 应用范围
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MTA1 抗体 by 抗体来源
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MTA1 抗体 by 克隆形成能力
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MTA1 抗体 by 克隆
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MTA1 抗体 by 标记
Find MTA1 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular MTA1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (7)
Cat. No.
ABIN522561
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (6)
Cat. No.
ABIN563943
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN522563
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN7193370
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (4)
Cat. No.
ABIN686182
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p), IF, ICC
Validations
- (4)
Cat. No.
ABIN2854809
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193369
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257333
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN184623
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881556
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN522560
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN3044412
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN5013926
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN522562
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN203133
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our MTA1 抗体
: "Metastasis-associated protein 1/histone deacetylase 4-nucleosome remodeling and deacetylase complex regulates phosphatase and tensin homolog gene expression and function." in: The Journal of biological chemistry, Vol. 287, Issue 33, pp. 27843-50, (2012) (PubMed).: "MTA1 coregulation of transglutaminase 2 expression and function during inflammatory response." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7132-8, (2011) (PubMed).
: "TGF-β1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells." in: Oncogene, Vol. 30, Issue 19, pp. 2230-41, (2011) (PubMed).
: "Metastasis-associated protein 1 nuclear expression is associated with tumor progression and clinical outcome in patients with non-small cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 5, Issue 8, pp. 1159-66, (2010) (PubMed).
: "Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells." in: Molecular and cellular biology, Vol. 30, Issue 16, pp. 4045-59, (2010) (PubMed).
: "[Expression of Mta-1 and VEGF and their correlation in the endometrial cancer]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 7, pp. 682-4, (2010) (PubMed).
: "Requirement of MTA1 in ATR-mediated DNA damage checkpoint function." in: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 19802-12, (2010) (PubMed).
: "Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 10044-52, (2010) (PubMed).
: "MTA1 coregulator regulates LPS response via MyD88-dependent signaling." in: The Journal of biological chemistry, Vol. 285, Issue 43, pp. 32787-92, (2010) (PubMed).
: "MTA1 coregulator regulates p53 stability and function." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34545-52, (2009) (PubMed).
Aliases for MTA1 抗体
metastasis associated 1 (MTA1) 抗体metastasis associated 1 (Mta1) 抗体
metastasis associated 1 L homeolog (mta1.L) 抗体
Tex22 抗体
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