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MSH3 产品

(MutS Homolog 3 (MSH3))

Categories

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011].

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Featured MSH3 Categories

MSH3 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our MSH3 Products

Amaral-Silva, Sánchez-Romero, Wagner, Martins, Pontes, Fregnani, Soares, Almeida, Rocha, Santos-Silva, Fonseca, Vargas: "Prognostic significance of hMSH2, hMSH3, and hMSH6 expression in ameloblastoma." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 124, Issue 3, pp. 286-295, (2017) (PubMed).

Wilson, Guerrette, Fishel: "Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21659-64, (1999) (PubMed).

Umar, Risinger, Glaab, Tindall, Barrett, Kunkel: "Functional overlap in mismatch repair by human MSH3 and MSH6." in: Genetics, Vol. 148, Issue 4, pp. 1637-46, (1998) (PubMed).

Watanabe, Ikejima, Suzuki, Shimada: "Genomic organization and expression of the human MSH3 gene." in: Genomics, Vol. 31, Issue 3, pp. 311-8, (1997) (PubMed).

New, Liu, Crouse: "The yeast gene MSH3 defines a new class of eukaryotic MutS homologues." in: Molecular & general genetics : MGG, Vol. 239, Issue 1-2, pp. 97-108, (1993) (PubMed).

Synonyms and alternative names related to MSH3

mutS homolog 3 (MSH3), mutS homolog 3 (Msh3), DNA mismatch repair protein MSH3 (MSH3), homolog of DNA mismatch repair protein MSH3 (MSH3), mismatch repair protein (MSH3), ATMSH3, D13Em1, DUP, homolog of DNA mismatch repair protein MSH3, M7J2.90, M7J2_90, MRP1, Rep-3, Rep3

Protein level used designations for MSH3

  • DNA mismatch repair protein Msh3
  • DNA mismatch repair protein MSH3
  • hypothetical protein
  • divergent upstream protein
  • hMSH3
  • mismatch repair protein 1
  • REP-1
  • protein repair-1
  • protein repair-3
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