MRPL12 产品
(Mitochondrial Ribosomal Protein L12 (MRPL12))
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008].
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Recommended MRPL12 抗体
Product
Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), RNAi
Validations
- (3)
- (7)
Cat. No.
ABIN562710
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN948420
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7142352
Quantity
100 μL
Datasheet
Datasheet
Recommended MRPL12 蛋白
Latest Publications for our MRPL12 Products
: "A bifunctional protein regulates mitochondrial protein synthesis." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5483-94, (2014) (PubMed).: "Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect." in: PLoS ONE, Vol. 4, Issue 9, pp. e7033, (2009) (PubMed).
: "Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12610-8, (2007) (PubMed).
Synonyms and alternative names related to MRPL12
mitochondrial ribosomal protein L12 (MRPL12), 39S ribosomal protein L12, mitochondrial (LOC409926), mitochondrial nucleoid protein (CAALFM_C207190CA), mitochondrial ribosomal protein L12 (Mrpl12), mitochondrial ribosomal protein L12 (mrpl12), mitochondrial ribosomal protein L12 L homeolog (mrpl12.L), 5c5-2, 0610034O11Rik, 1500031N16Rik, GB14723, im:6893415, L12mt, MRP-L12, MRP-L31/34, MRPL7, MRPL7/L12, MRPL12, mrpl12, Rpm12, RPML12, Rpml12, zgc:112445Protein level used designations for MRPL12
- 39S ribosomal protein L12, mitochondrial
- MRP-L12
- mitochondrial ribosomal protein L12
- likely mitochondrial ribosomal protein (E. coli L7/L12)
- L12mt
- ribosomal protein, mitochondrial, L12
- mitochondrial ribosomal protein L12 L homeolog
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