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MPL ELISA试剂盒

(Myeloproliferative Leukemia Virus Oncogene (MPL))

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated. [provided by RefSeq, Jul 2008].

recommended

MPL ELISA 试剂盒 (ABIN6957947)

MPL 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate

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recommended

MPL ELISA 试剂盒 (ABIN5510636)

MPL 适用: 小鼠 AA 26-482 Colorimetric Sandwich ELISA

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recommended

MPL ELISA 试剂盒 (ABIN1117542)

MPL 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Plasma, Serum

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MPL ELISA试剂盒 by 适用

Find MPL ELISA试剂盒 for a variety of species such as anti-Human MPL, anti-Mouse MPL, anti-Rat MPL. The species listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA试剂盒 by 检测方法

Find MPL ELISA试剂盒 with a specific 检测方法. The 检测方法 listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA试剂盒 by Analytical Method

Find MPL ELISA试剂盒 with a specific Analytical Method. The Analytical Method listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA试剂盒 by 实验类型

Find MPL ELISA试剂盒 with a specific 实验类型. The 实验类型 listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA试剂盒 by 样本

Find MPL ELISA试剂盒 with a specific 样本. The 样本 listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA试剂盒 by 抗原表位

Find MPL ELISA试剂盒 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Popular MPL ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

MPL ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6957947

Quantity 96 tests

Datasheet Datasheet

MPL ELISA 试剂盒

Reactivity Mouse

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN5510636

Quantity 96 tests

Datasheet Datasheet

MPL ELISA 试剂盒

Reactivity Rat

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN1117542

Quantity 96 tests

Datasheet Datasheet

MPL ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6951177

Quantity 96 tests

Datasheet Datasheet

MPL ELISA 试剂盒

Reactivity Mouse

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6730219

Quantity 96 tests

Datasheet Datasheet

Aliases for MPL ELISA试剂盒

MPL proto-oncogene, thrombopoietin receptor (MPL) ELISA试剂盒
myeloproliferative leukemia virus oncogene (Mpl) ELISA试剂盒
MPL proto-oncogene, thrombopoietin receptor (Mpl) ELISA试剂盒
MPL proto-oncogene, thrombopoietin receptor (mpl) ELISA试剂盒
C-MPL ELISA试剂盒
c-mpl ELISA试剂盒
c-mpl-I ELISA试剂盒
c-mpl-II ELISA试剂盒
CD110 ELISA试剂盒
hlb219 ELISA试剂盒
MPL ELISA试剂盒
mpll ELISA试剂盒
MPLV ELISA试剂盒
THCYT2 ELISA试剂盒
TPO-R ELISA试剂盒
TPOR ELISA试剂盒
tpor ELISA试剂盒
tpor.b ELISA试剂盒

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MPL ELISA试剂盒 by 适用

MPL ELISA试剂盒 by 检测方法

MPL ELISA试剂盒 by Analytical Method

MPL ELISA试剂盒 by 实验类型

MPL ELISA试剂盒 by 样本

MPL ELISA试剂盒 by 抗原表位

Popular MPL ELISA试剂盒

Aliases for MPL ELISA试剂盒

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