MOB1A 产品
(MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
Categories
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 (By similarity).
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Featured MOB1A Categories
Recommended MOB1A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF, IP
Validations
- (5)
Cat. No.
ABIN7160116
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542651
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542650
Quantity
100 μL
Datasheet
Datasheet
Recommended MOB1A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124011
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311121
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7318782
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our MOB1A Products
: "Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis." in: Molecular biology of the cell, Vol. 21, Issue 3, pp. 380-92, (2010) (PubMed).Synonyms and alternative names related to MOB1A
MOB kinase activator 1A L homeolog (mob1a.L), MOB kinase activator 1A (MOB1A), MOB kinase activator 1A (mob1a), MOB kinase activator 1A pseudogene (LOC712156), MOB kinase activator 1A (Mob1a), 4022402H07Rik, C2orf6, mats1, MATS1, mob1, MOB1, MOB1A, mob4b, Mob4B, MOB4B, MOBK1B, mobk1b, Mobk1b, mobkl1b, MOBKL1B, Mobkl1b, wu:fv69d04, zgc:56189Protein level used designations for MOB1A
- MOB1, Mps One Binder kinase activator-like 1B
- Mob4B protein
- mps one binder kinase activator-like 1B
- MOB1, Mps One Binder kinase activator-like 1B (yeast)
- mats1
- mobk1b
- Mps one binder kinase activator-like 1B
- mob1 homolog 1B
- MOB1 Mps One Binder homolog A
- mob1 alpha
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