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MMP8 产品

(Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))

Categories

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].

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Featured MMP8 Categories

MMP8 抗体

High quality antibodies with extensive validation data.

MMP8 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MMP8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MMP8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7425689
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IP, ICC, IF
Validations
  • (4)
Cat. No. ABIN2856104
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7242290
Quantity 200 μL
Datasheet Datasheet

Recommended MMP8 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6957713
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6957714
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963732
Quantity 96 tests
Datasheet Datasheet

Recommended MMP8 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275269
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275265
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275273
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MMP8 Products

Sîrbulescu, Boehm, Soon, Wilks, Ilieş, Yuan, Maxner, Chronos, Kaittanis, Normandin, El Fakhri, Orgill, Sluder, Poznansky: "Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 25, Issue 5, pp. 774-791, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Kumar, Jain, Chauhan, Bharate, Koli, Kumar: "Influence of different forms and materials (zirconia or titanium) of abutments in periimplant soft-tissue healing using matrix metalloproteinase-8: A randomized pilot study." in: The Journal of prosthetic dentistry, (2017) (PubMed).

Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." in: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

Carbone, Crowe, Roth, Burger, Lenglet, Braunersreuther, Brandt, Quercioli, Mach, Vallée, Montecucco: "Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury." in: Journal of molecular and cellular cardiology, Vol. 94, pp. 82-94, (2016) (PubMed).

Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).

Oralova, Matalova, Killinger, Knopfova, Smarda, Buchtova: "Osteogenic Potential of the Transcription Factor c-MYB." in: Calcified tissue international, Vol. 100, Issue 3, pp. 311-322, (2016) (PubMed).

Da Silva, Lenglet, Carbone, Burger, Roth, Liberale, Bonaventura, Dallegri, Stergiopulos, Santos, Mach, Fraga-Silva, Montecucco: "Alamandine abrogates neutrophil degranulation in atherosclerotic mice." in: European journal of clinical investigation, Vol. 47, Issue 2, pp. 117-128, (2016) (PubMed).

Aral, Kesim, Greenwell, Kara, Çetin, Yakan: "Alveolar bone protective and hypoglycemic effects of systemic propolis treatment in experimental periodontitis and diabetes mellitus." in: Journal of medicinal food, Vol. 18, Issue 2, pp. 195-201, (2015) (PubMed).

Stio, Martinesi, Treves, Borgioli: "In vitro response of human peripheral blood mononuclear cells to AISI 316L austenitic stainless steel subjected to nitriding and collagen coating treatments." in: Journal of materials science. Materials in medicine, Vol. 26, Issue 2, pp. 100, (2015) (PubMed).

Synonyms and alternative names related to MMP8

matrix metallopeptidase 8 (MMP8), matrix metallopeptidase 8 (Mmp8), neutrophil collagenase (LOC100339790), BB138268, CLG1, HNC, MMP-8, MMP8, PMNL-CL

Protein level used designations for MMP8

  • matrix metallopeptidase 8 (neutrophil collagenase)
  • matrix metalloproteinase 8
  • MMP-8
  • collagenase 2
  • collagenase-2
  • matrix metalloproteinase-8
  • neutrophil collagenase
  • neutrophil collagenease
  • PMNL collagenase
  • matrix metalloproteinase 8 (neutrophil collagenase)
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