MME 产品
(Membrane Metallo-Endopeptidase (MME))
Categories
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008].
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Featured MME Categories
MME 抗体
High quality antibodies with extensive validation data.
MME ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MME 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MME 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (6)
Cat. No.
ABIN6143900
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN1724914
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
Validations
- (1)
- (5)
Cat. No.
ABIN669666
Quantity
100 μL
Datasheet
Datasheet
Recommended MME ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (4)
Cat. No.
ABIN6730947
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957745
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957744
Quantity
96 tests
Datasheet
Datasheet
Recommended MME 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275263
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275264
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275262
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MME Products
: "Increased granulocyte membrane neprilysin (CD10) expression is associated with better prognosis in heart failure." in: European journal of heart failure, Vol. 21, Issue 4, pp. 537-539, (2020) (PubMed).: "Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)." in: Clinical research in cardiology : official journal of the German Cardiac Society, Vol. 109, Issue 8, pp. 1035-1047, (2020) (PubMed).
: "Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression." in: Phytotherapy research : PTR, Vol. 33, Issue 4, pp. 1114-1121, (2019) (PubMed).
: "Cinacalcet attenuated bone loss via inhibiting parathyroid hormone-induced endothelial-to-adipocyte transition in chronic kidney disease rats." in: Annals of translational medicine, Vol. 7, Issue 14, pp. 312, (2019) (PubMed).
: "Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report." in: Experimental and therapeutic medicine, Vol. 16, Issue 3, pp. 2060-2065, (2018) (PubMed).
: "Improved glycaemia in high-fat-fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels." in: Diabetologia, Vol. 60, Issue 4, pp. 701-708, (2017) (PubMed).
: "Soluble neprilysin does not correlate with outcome in heart failure with preserved ejection fraction." in: European journal of heart failure, Vol. 18, Issue 1, pp. 89-93, (2016) (PubMed).
: "A Test in Context: Neprilysin: Function, Inhibition, and Biomarker." in: Journal of the American College of Cardiology, Vol. 68, Issue 6, pp. 639-53, (2016) (PubMed).
: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).
Synonyms and alternative names related to MME
membrane metalloendopeptidase (MME), membrane metallo endopeptidase (Mme), membrane metallo-endopeptidase (Mme), membrane metalloendopeptidase (Mme), 6030454K05Rik, C85356, CALLA, CD10, NEP, Nep, neprilysin, SFEProtein level used designations for MME
- atriopeptidase
- common acute lymphocytic leukemia antigen
- enkephalinase
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
- membrane metallo-endopeptidase variant 1
- membrane metallo-endopeptidase variant 2
- neprilysin
- neutral endopeptidase 24.11
- skin fibroblast elastase
- common acute lymphoblastic leukemia antigen
- neutral endopeptidase
- neprilysin-410 short isoform
- membrane metallo endopeptidase
- NEP
- membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase)
- LOW QUALITY PROTEIN: neprilysin
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