MLL3 抗体
(Histone-lysine N-methyltransferase 2C (KMT2C))
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008].
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Latest Publications for our MLL3 Products
: "Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer." in: Biochimica et biophysica acta, Vol. 1849, Issue 6, pp. 697-708, (2015) (PubMed).: "Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo." in: The Journal of steroid biochemistry and molecular biology, Vol. 141, pp. 160-70, (2014) (PubMed).
: "Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol." in: Journal of molecular biology, Vol. 425, Issue 19, pp. 3707-22, (2013) (PubMed).
: "HOXC10 is overexpressed in breast cancer and transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4." in: Journal of molecular endocrinology, Vol. 48, Issue 1, pp. 61-75, (2012) (PubMed).
: "HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment." in: Journal of molecular biology, Vol. 411, Issue 2, pp. 334-49, (2011) (PubMed).
: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 140-9, (2002) (PubMed).
Synonyms and alternative names related to MLL3
lysine methyltransferase 2C (KMT2C), lysine (K)-specific methyltransferase 2C (Kmt2c), E330008K23Rik, HALR, mKIAA1506, MLL3, Mll3Protein level used designations for MLL3
- ALR-like protein
- histone-lysine N-methyltransferase 2C
- histone-lysine N-methyltransferase MLL3
- histone-lysine N-methyltransferase, H3 lysine-4 specific
- homologous to ALR protein
- lysine N-methyltransferase 2C
- myeloid/lymphoid or mixed-lineage leukemia 3
- myeloid/lymphoid or mixed-lineage leukemia protein 3
- myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
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