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MLL/KMT2A 蛋白

(Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010].

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MLL/KMT2A Protein (AA 3735-3973) (GST tag) (ABIN6579161)

MLL 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant EAA, ScA

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MLL/KMT2A 蛋白 by Origin

Find MLL/KMT2A 蛋白 for a variety of species such as anti-Human MLL/KMT2A. The species listed below are among those available. Click on a link to go to the corresponding products.

MLL/KMT2A 蛋白 by Source

Here you will find MLL/KMT2A 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MLL/KMT2A 蛋白 by 蛋白类型

Here you can find MLL/KMT2A 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

MLL/KMT2A 蛋白 by 应用范围

Find MLL/KMT2A 蛋白 validated for a specific application such as EAA, ScA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MLL/KMT2A 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MLL/KMT2A Protein (AA 3735-3973) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6579161

Quantity 50 μg

Datasheet Datasheet

Aliases for MLL/KMT2A 蛋白

lysine methyltransferase 2A (KMT2A) 蛋白
lysine (K)-specific methyltransferase 2A (Kmt2a) 蛋白
lysine methyltransferase 2A (Kmt2a) 蛋白
6430520K01 蛋白
ALL-1 蛋白
All1 蛋白
CXXC7 蛋白
Cxxc7 蛋白
HRX 蛋白
HTRX1 蛋白
mKIAA4050 蛋白
MLL 蛋白
Mll 蛋白
MLL/GAS7 蛋白
Mll1 蛋白
MLL1A 蛋白
TET1-MLL 蛋白
TRX1 蛋白
WDSTS 蛋白

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