MKL1 产品
(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
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The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq, Jul 2008].
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MKL1 抗体
High quality antibodies with extensive validation data.
Recommended MKL1 抗体
Product
Reactivity
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Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
Cat. No.
ABIN6143855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN1387286
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6259116
Quantity
100 μL
Datasheet
Datasheet
Recommended MKL1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968520
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our MKL1 Products
: "Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas." in: Nature medicine, Vol. 24, Issue 3, pp. 271-281, (2018) (PubMed).: "Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices." in: Scientific reports, Vol. 5, pp. 11458, (2015) (PubMed).
: "Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1." in: Blood, Vol. 126, Issue 13, pp. 1527-35, (2015) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "RhoA as a mediator of clinically relevant androgen action in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 5, pp. 716-35, (2012) (PubMed).
: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." in: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).
Synonyms and alternative names related to MKL1
megakaryoblastic leukemia (translocation) 1 (MKL1), megakaryoblastic leukemia 1 protein (mkl1), megakaryoblastic leukemia (translocation) 1 (Mkl1), megakaryoblastic leukemia (translocation) 1 S homeolog (mkl1.S), MKL (megakaryoblastic leukemia)/myocardin-like 1 (Mkl1), AI852829, AMKL, AW743281, AW821984, BSAC, Bsac, MAL, Mal, MKL1, MRTF-A, Mrtf-a, mrtf-a, Mrtf-A, mrtfaProtein level used designations for MKL1
- megakaryoblastic leukemia 1 protein
- MKL/myocardin-like protein 1
- RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein
- basic, SAP and coiled-coil domain
- megakaryocytic acute leukemia protein
- myocardin-related transcription factor A
- xMRTF-A
- basic SAP and coiled-coil domains
- basic SAP coiled-coil transcription activator
- megakaryoblastic leukemia (translocation) 1 homolog
- megakaryoblastic leukemia 1 protein homolog
您还需要查找其他产品吗？
- MKL
- MKKS
- MK13
- MK03
- MIXL1
- Mitogen-Activated Protein Kinase Kinase Kinase 3
- Mitogen-Activated Protein Kinase Kinase Kinase 13
- Mitogen-Activated Protein Kinase Kinase 4
- Mitogen-Activated Protein Kinase Kinase 2
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase
- Mitochondrially Encoded NADH Dehydrogenase 4
- Mitochondrially Encoded ATP Synthase 8
- Mitochondrial Translation Elongation Factor EF-Ts Tsf1
- Mitochondrial Import Receptor Subunit TOM20 homolog
- Mitochondrial E3 Ubiquitin Protein Ligase 1
- Mitochondrial ATPase Subunit 8
- MITF
- MITD1
- Mismatch Repair Protein 2
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