Mitogen-Activated Protein Kinase Kinase 2 抗体
(Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
recommended
MEK2 抗体 (AA 1-50) (ABIN726500)
MAP2K2 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Popular Mitogen-Activated Protein Kinase Kinase 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (1)
Cat. No.
ABIN726500
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7439504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (5)
- (3)
Cat. No.
ABIN1882178
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF
Validations
- (4)
Cat. No.
ABIN519254
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN948323
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7268640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN392485
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (5)
- (4)
Cat. No.
ABIN1881526
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7150701
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7138844
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN6243254
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IP, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263216
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IP, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256556
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1499478
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC
Validations
- (3)
Cat. No.
ABIN1724726
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Mitogen-Activated Protein Kinase Kinase 2 抗体
: "Follicular fluid meiosis-activating sterol (FF-MAS) promotes meiotic resumption via the MAPK pathway in porcine oocytes." in: Theriogenology, (2019) (PubMed).: "The MEK/ERK cascade: from signaling specificity to diverse functions." in: Biochimica et biophysica acta, Vol. 1773, Issue 8, pp. 1213-26, (2007) (PubMed).
: "Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18574-9, (2006) (PubMed).
: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, (2003) (PubMed).
: "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7177-88, (2003) (PubMed).
: "p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2." in: Cancer research, Vol. 63, Issue 13, pp. 3473-7, (2003) (PubMed).
: "The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13663-71, (2003) (PubMed).
Aliases for Mitogen-Activated Protein Kinase Kinase 2 抗体
mitogen-activated protein kinase kinase 2 (MAP2K2) 抗体mitogen-activated protein kinase kinase 2 (Map2k2) 抗体
mitogen activated protein kinase kinase 2 (Map2k2) 抗体
MAP kinase kinase 2 (MKK2) 抗体
mitogen-activated protein kinase kinase 2a (map2k2a) 抗体
mitogen-activated protein kinase kinase 2b (map2k2b) 抗体
AA589381 抗体
ATMKK2 抗体
CFC4 抗体
F27B13.50 抗体
F27B13_50 抗体
map2k2 抗体
MAP KINASE KINASE 1 抗体
MAP kinase kinase 2 抗体
MAPKK2 抗体
MEK2 抗体
MK1 抗体
MK2 抗体
MKK2 抗体
PRKMK2 抗体
Prkmk2 抗体
wu:fa56c06 抗体
zgc:123171 抗体
zgc:172250 抗体
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