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Mitogen-Activated Protein Kinase 抗体

(Mitogen-Activated Protein Kinase (MAPK))
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The the MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Many of the substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC)\; as well as in the fragmentation of the Golgi apparatus during mitosis. Phosphorylates microtubule-associated protein 2 (MAP2), myelin basic protein (MBP), and Elk-1. Activated by M phase promoting factor (MPF).
Mitogen-Activated Protein Kinase (MAPK) (pThr202), (pTyr204) 抗体 (ABIN2473488)

MAPK 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 猴, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

Mitogen-Activated Protein Kinase (MAPK) (N-Term) 抗体 (ABIN347177)

MAPK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

Mitogen-Activated Protein Kinase (MAPK) 抗体 (ABIN2928448)

MAPK 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Mitogen-Activated Protein Kinase 抗体 by 适用

Find Mitogen-Activated Protein Kinase 抗体 for a variety of species such as anti-Human Mitogen-Activated Protein Kinase, anti-Mouse Mitogen-Activated Protein Kinase, anti-Rat Mitogen-Activated Protein Kinase. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Mitogen-Activated Protein Kinase 抗体 validated for a specific application such as WB, ELISA, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Mitogen-Activated Protein Kinase 抗体 by 抗原表位

Find Mitogen-Activated Protein Kinase 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Popular Mitogen-Activated Protein Kinase 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB
Validations
Cat. No. ABIN2473488
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
Cat. No. ABIN347177
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN2928448
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
Cat. No. ABIN5688866
Quantity 0.1 mL
Datasheet Datasheet

Latest Publications for our Mitogen-Activated Protein Kinase 抗体

Cseh, Doma, Baccarini: ""RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway." in: FEBS letters, Vol. 588, Issue 15, pp. 2398-406, (2014) (PubMed).

Tanoue, Nishida: "Molecular recognitions in the MAP kinase cascades." in: Cellular signalling, Vol. 15, Issue 5, pp. 455-62, (2003) (PubMed).

Johnson, Lapadat: "Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases." in: Science (New York, N.Y.), Vol. 298, Issue 5600, pp. 1911-2, (2002) (PubMed).

Adams, Sweatt: "Molecular psychology: roles for the ERK MAP kinase cascade in memory." in: Annual review of pharmacology and toxicology, Vol. 42, pp. 135-63, (2002) (PubMed).

Aliases for Mitogen-Activated Protein Kinase 抗体

mitogen-activated protein kinase (Tc00.1047053506229.10) 抗体
mitogen-activated protein kinase (Tb927.6.1780) 抗体
mitogen-activated protein kinase (Tb927.8.3770) 抗体
mitogen-activated protein kinase 1 S homeolog (mapk1.S) 抗体
erk 抗体
erk2 抗体
ert1 抗体
mapk 抗体
mapk1 抗体
mapk1a 抗体
mapk2 抗体
mpk1 抗体
p42mapk 抗体
prkm1 抗体
prkm2 抗体
Tb06.28P18.710 抗体
Tb08.10J17.560 抗体
xp42 抗体
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