Minichromosome Maintenance Deficient 4 抗体
(Minichromosome Maintenance Deficient 4 (MCM4))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
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Minichromosome Maintenance Deficient 4 抗体 by 适用
Find Minichromosome Maintenance Deficient 4 抗体 for a variety of species such as anti-Human Minichromosome Maintenance Deficient 4, anti-Mouse Minichromosome Maintenance Deficient 4, anti-Rat Minichromosome Maintenance Deficient 4. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find available monoclonal or polyclonal Minichromosome Maintenance Deficient 4 抗体. Click on a link to go to the corresponding products.
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Popular Minichromosome Maintenance Deficient 4 抗体
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Cat. No.
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Quantity
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Quantity
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Bat, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN630173
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
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Latest Publications for our Minichromosome Maintenance Deficient 4 抗体
: "Cohesin acetylation promotes sister chromatid cohesion only in association with the replication machinery." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34325-36, (2012) (PubMed).: "Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle." in: Oncogene, Vol. 29, Issue 26, pp. 3803-14, (2010) (PubMed).
: "Expression, nuclear localization and interactions of human MCM/P1 proteins." in: Biochemical and biophysical research communications, Vol. 236, Issue 1, pp. 118-25, (1997) (PubMed).
: "A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins." in: European journal of biochemistry / FEBS, Vol. 230, Issue 3, pp. 1096-101, (1995) (PubMed).
: "The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins." in: Nucleic acids research, Vol. 21, Issue 23, pp. 5289-93, (1994) (PubMed).
: "Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication." in: Nucleic acids research, Vol. 20, Issue 21, pp. 5571-7, (1993) (PubMed).
: "A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication." in: Nucleic acids research, Vol. 21, Issue 11, pp. 2541-7, (1993) (PubMed).
Aliases for Minichromosome Maintenance Deficient 4 抗体
minichromosome maintenance complex component 4 L homeolog (mcm4.L) 抗体minichromosome maintenance complex component 4 S homeolog (mcm4.S) 抗体
minichromosome maintenance complex component 4 (MCM4) 抗体
minichromosome maintenance complex component 4 (mcm4) 抗体
minichromosome maintenance complex component 4 (Mcm4) 抗体
19G 抗体
AI325074 抗体
AU045576 抗体
cb1025 抗体
cdc21 抗体
CDC21 抗体
Cdc21 抗体
CDC54 抗体
fc12c09 抗体
fj85g09 抗体
hCdc21 抗体
hm:zeh1616 抗体
mcdc21 抗体
Mcmd4 抗体
mKIAA4003 抗体
NKCD 抗体
NKGCD 抗体
P1-CDC21 抗体
wu:fc12c09 抗体
wu:fj85g09 抗体
zeh1616 抗体
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