Minichromosome Maintenance Complex Component 3 产品
(Minichromosome Maintenance Complex Component 3 (MCM3))
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
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Minichromosome Maintenance Complex Component 3 抗体
High quality antibodies with extensive validation data.
Minichromosome Maintenance Complex Component 3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Minichromosome Maintenance Complex Component 3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Minichromosome Maintenance Complex Component 3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (11)
Cat. No.
ABIN561761
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (7)
Cat. No.
ABIN3021327
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN7268540
Quantity
100 μL
Datasheet
Datasheet
Recommended Minichromosome Maintenance Complex Component 3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957841
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656914
Quantity
96 tests
Datasheet
Datasheet
Recommended Minichromosome Maintenance Complex Component 3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1310549
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505054
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420189
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Minichromosome Maintenance Complex Component 3 Products
: "Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells." in: Toxicology letters, Vol. 209, Issue 1, pp. 58-66, (2012) (PubMed).: "High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma." in: Diagnostic pathology, Vol. 7, pp. 82, (2012) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." in: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).
: "BID binds to replication protein A and stimulates ATR function following replicative stress." in: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4298-309, (2011) (PubMed).
: "Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24." in: Blood, Vol. 111, Issue 10, pp. 5215-22, (2008) (PubMed).
Synonyms and alternative names related to Minichromosome Maintenance Complex Component 3
minichromosome maintenance complex component 3 (MCM3), MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) (mcm3), minichromosome maintenance complex component 3 (mcm3), minichromosome maintenance complex component 3 (Mcm3), Minichromosome maintenance 3 (Mcm3), minichromosome maintenance complex component 3 L homeolog (mcm3.L), MCM complex subunit Mcm3 (mcm3), AL033361, C80350, cb32, CG4206, chunp6867, dMCM3, Dmel\\CG4206, DmeMCM3, DmMCM3, DmMcm3, HCC5, MCM3, McM3, Mcmd, Mcp-PCR2, P1, P1-MCM3, P1.h, p1.m, PCR2, RLFB, wu:fa26g03, xmcm3Protein level used designations for Minichromosome Maintenance Complex Component 3
- DNA polymerase alpha holoenzyme-associated protein P1
- DNA replication factor MCM3
- DNA replication licensing factor MCM3
- MCM3 minichromosome maintenance deficient 3
- RLF subunit beta
- cervical cancer proto-oncogene 5
- hRlf beta subunit
- minichromosome maintenance deficient 3
- p102
- replication licensing factor, beta subunit
- zMCM3
- zygotic DNA replication licensing factor mcm3
- zygotic minichromosome maintenance protein 3
- P1-MCM3
- mini chromosome maintenance deficient
- CG4206-PA
- Mcm3-PA
- minichromosome maintenance 3
- minichromosome maintenance-PCR2
- P1 homolog
- XRLF subunit beta
- mMCM3
- maternal DNA replication licensing factor mcm3
- maternal minichromosome maintenance protein 3
- p100
- Minichromosome maintenance protein 3
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