MICU1 产品
(Mitochondrial Calcium Uptake 1 (MICU1))
Categories
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013].
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Featured MICU1 Categories
MICU1 抗体
High quality antibodies with extensive validation data.
MICU1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MICU1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MICU1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN7206382
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF
Validations
- (3)
Cat. No.
ABIN7250269
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7178517
Quantity
100 μg
Datasheet
Datasheet
Recommended MICU1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968632
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1124747
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1124748
Quantity
96 tests
Datasheet
Datasheet
Recommended MICU1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348155
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348154
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093898
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MICU1 Products
: "Cytosolic and mitochondrial Ca2+ concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation." in: Cell calcium, Vol. 82, pp. 102055, (2019) (PubMed).: "MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca(2+)-Dependent Antioxidant Response." in: Diabetes, Vol. 66, Issue 6, pp. 1586-1600, (2017) (PubMed).
: "MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload." in: Cell reports, Vol. 16, Issue 6, pp. 1561-73, (2016) (PubMed).
: "Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells." in: Cancer letters, Vol. 358, Issue 1, pp. 47-58, (2015) (PubMed).
: "Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter." in: EMBO reports, Vol. 16, Issue 10, pp. 1318-33, (2015) (PubMed).
: "Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. ..." in: Nature genetics, Vol. 46, Issue 2, pp. 188-93, (2014) (PubMed).
: "Directed evolution of APEX2 for electron microscopy and proximity labeling." in: Nature methods, Vol. 12, Issue 1, pp. 51-4, (2014) (PubMed).
: "Dynamics of mitochondrial Ca2+ uptake in MICU1-knockdown cells." in: The Biochemical journal, Vol. 458, Issue 1, pp. 33-40, (2014) (PubMed).
Synonyms and alternative names related to MICU1
mitochondrial calcium uptake 1 (MICU1), mitochondrial calcium uptake 1 (Micu1), C730016L05Rik, CALC, Calc, CBARA1, Cbara1, EFHA3Protein level used designations for MICU1
- ara CALC
- atopy-related autoantigen CALC
- calcium uptake protein 1, mitochondrial
- calcium-binding atopy-related autoantigen 1
- calcium binding atopy-related autoantigen 1
- calcium-binding atopy-related autoantigen 1 homolog
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